Synonyms: Carboxyl benzophenone alkyne; Probe building block
Molecular Formula: C17H12O4
Molecular Weight: 280.27
Linear Structural Formula: C17H12O4
MDL Number: MFCD21648478
Purity: >=95%
Storage: -20C
Application: 4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes: Technology Spotlight: Trifuctional Probe Building BlocksA library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpSSynthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase