Synonyms: Amino (PEG)3 benzophenone alkyne HCl salt; Probe building block
Molecular Formula: C22H25NO5 · HCl
Molecular Weight: 419.9
Linear Structural Formula: C22H25NO5 · HCl
Purity: >=95%
Storage: -20C
Application: (4-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone HCl salt is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its PEGylated amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes: Technology Spotlight: Trifuctional Probe Building BlocksA library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpSInvestigating gamma-secretase protein interactions in live cells using active site-directed clickable dual-photoaffinity probes