Synonyms: 3-((2-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)disulfaneyl)propanoic acid; Biotin-SS-COOH; Cleavable biotin linker
Molecular Formula: C15H25N3O4S3
Molecular Weight: 407.57
Linear Structural Formula: C15H25N3O4S3
MDL Number: MFCD04039425
Purity: >=95%
Melting Point: 172-175 C
Storage: -20C
Application: 3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid (Biotin-SS-COOH) is a cleavable, biotinylated crosslinkers. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions.
Other Notes: Uniformly Cationized Protein Efficiently Reaches the Cytosol of Mammalian CellsA Mechanism-Based ICAT Strategy for Comparing Relative Expression and Activity Levels of Glycosidases in Biological SystemsDissociation-independent selection of high-affinity anti-hapten phage antibodies using cleavable biotin-conjugated haptens