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MilliporeSigma

(2R)-2-Phenyl-3,4-dihydro-2H-pyrimido[2,1-b][1,3]benzothiazole >=95%

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Synonyms: (R)-2-Phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine; (R)-Homobenzotetramisole; Birman (R)-HBTM

Molecular Formula: C16H14N2S

Molecular Weight: 266.36

Linear Structural Formula: C16H14N2S

MDL Number: MFCD26793803

Purity: >=95%

Melting Point: 145-147 C

Storage: 2-8C

Application: This chiral isothiourea homobenzotetramisole ((R)-HBTM) developed by the Birman lab is an organocatalyst that has been used for kinetic resolution, determination of absolute configuration, and nucleophile-catalysed, Michael–aldol-b-lactonization (NCMAL). This same product was previously listed as L511730, and the complementary (S)-HBTM organocatalyst (900542) is also available.

Other Notes: Technology Spotlight: Homobenzotetramisole (HBTM): A General Organocatalyst for Asymmetric Acylations[1] Determination of the Absolute Configuration beta-Chiral Primary Alcohols Using the Competing Enantioselective Conversion Method[2] Asymmetric Catalytic Synthesis of Thiochromenes via an Acyl Transfer-Initiated Cascade[3] Rapid assembly of complex cyclopentanes employing chiral, alpha, beta-unsaturated acylammonium intermediates[4] Determination of Absolute Configuration Using Kinetic Resolution Catalysts[5] Kinetic Resolution of Secondary Alcohols Using Amidine-Based Catalysts

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Product Detail
Thomas No.
CHM02K742
Mfr. No.
901233-100MG
Description
901233-100MG, (2R)-2-Phenyl-3,4-dihydro-2H-pyrimido[2,1-b][1,3]benzothiazole >=95%
CAS Number
1316861-19-4
Packaging Size
100 MG
list price/quantitytotal
$0.00
$0.00 (0 Items)
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