Synonyms: Amino diazirine alkyne; Probe building block
Molecular Formula: C7H11N3
Molecular Weight: 137.18
Linear Structural Formula: C7H11N3
MDL Number: MFCD29918288
Purity: 95%
Storage: -20C
Application: 2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes: Technology Spotlight: Trifuctional Probe Building BlocksDesign and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling"Minimalist" Cyclopropene-Containing Photo-Cross-Linkers Suitable for Live-Cell Imaging and Affinity-Based Protein Labeling