Synonym(s): Z-Leu-Leu-Leu-aldehyde Formula: C26H41N3O5 Formula weight: 475.63 CAS Number: 133407-82-6 Harmonized Tariff Code:  2924.29

An analytical reference standard categorized as a racemic mixture of (-)-cannabidiol and (+)-cannabidiol; intended for research and forensic applications

A selective inhibitor of CaMKII, competitively blocking CaM binding to the kinase (Ki = 370 nM); inhibits histamine-induced aminopyrine uptake in parietal cells (IC₅₀ = 300 nM).

Synonym(s): H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt Formula: C50H71N13O12 Formula weight: 1046.19 CAS Number: 4474-91-3 Harmonized Tariff Code:  2937.19

A long chain saturated fatty acid ethyl ester found in small quantities in liverwort, C. concium.

A dehydration product of PGD2 formed by the elimination of the C-9 hydroxyl group; inhibits platelet aggregation (IC₅₀ ~ 5-10 nM); has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines.

A competitive inhibitor of 15-hydroxy PGDH; acts as an agonist on most EP receptor subtypes (Kd d~ 1 nM for isolated EP2 receptors); preserves the self-renewal properties while preventing the differentiation of hematopoietic stem cells during expansion in culture.

Synonyms: 1-(3,4-Dimethoxyphenethyl)-4-(3-phenylpropyl)piperazine dihydrochloride; AGY 94806; AGY94806; Cutamesine; SA 4503 Molecular Formula: C23H32N2O2 · 2HCl Molecular Weight: 441.43 Linear Structural Formula: C23H32N2O2 · 2HCl MDL Number: MFCD09842336 Purity: >=98% (HPLC) …

Cloprostenol is a synthetic PGF2α analog and a potent FP receptor agonist. (+)-15-epi Cloprostenol is the 15(S), or 15β-hydroxy enantiomer of (+)-cloprostenol. This epimer is less active by several orders of magnitude as an FP receptor ligand when compared to 15(R)-cloprostenol. However,…

AFC is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.

Synonym(s): Z-FA-FMK, Z-Phe-Ala-FMK Formula: C21H23N2O4F Formula weight: 386.42 CAS Number: 105637-38-5 Harmonized Tariff Code:  2924.29

A β-adrenergic receptor agonist with potent positive inotropic effects in vivo; strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions; strongly increases cardiac contractility.

A pan-caspase inhibitor that blocks apoptosis, prevents the production of cytokines, and inhibits T cell proliferation dose-dependently at 1-100 μM.

CAS Number: 444932-31-4 Molecular Formula: C₂₀H₁₉N₃O₄ Formula Weight: 365.4

Synonym(s): (4-Benzyl-piperazin-1-yl)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-ylmethylene)-amine Empirical Formula: C₂₃H₂₇N₅ Linear Formula: C₂₃H₂₇N₅ Formula Weight: 373.49 MDL Number: MFCD01827306 Purity: ≥98%…

An inhibitor of ethylene biosynthesis that, at 1 µM, blocks the activity of both ACSs and ACOs; reduces ethylene-mediated plant changes in growth and development; inhibits cystathionine γ-lyase (Ki = 10.5 μM) with slow- and tight-binding characteristics.

A membrane-permeable cationic dye that is a substrate for P-gp and is rapidly exported from cells with functional P-gp; also accumulates within mitochondria and can be used to both localize mitochondria and study their properties.

Synonym(s): O-(2-Acetamido-2-deoxy-D-glucopyranosylidenamino) N-phenylcarbamate Empirical Formula: C₁₅H₁₉N₃O₇ Linear Formula: C₁₅H₁₉N₃O₇ Formula Weight: 353.33 MDL Number: MFCD00145022 Purity: …

Anti-Bovine IgG F(ab')2 antibody is suitable for ELISA, western blot, and immunohistochemistry, as well as other assays requiring lot-to-lot consistency.

A reversible inhibitor of the cis-Golgi ArfGEF, GBF1 (IC₅₀ = 3.3 µM); induces rapid dissociation of COPI vesicle coat protein from Golgi membranes and disassembly of the Golgi and trans-Golgi network, preventing bidirectional transport of endocytic cargo.

Sulfuretin is an aurones flavonoid found in the extract of Rhus verniciflua. The Extract of Rhus verniciflua is known in the traditional medicine and scientific community to have anti-cancer properties.Sulfuretin, one of the major constituents of Rhus verniciflua extract was found to have…

A cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity; inhibits mouse macrophage metalloelastase MME/MMP-12 (IC₅₀ = 13 nM).

A nonpurine inhibitor of xanthine oxidoreductase (Ki = 0.7 nM) that has proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.

A fluorescent probe that can react with ONOO-, HOCl, and H2O2 in a similar manner to CBA, yet is formulated for improved solubility.

AMT is a potent, relatively selective inhibitor of iNOS with a Ki of 4.2 nM in mouse macrophages. It inhibits other isoforms of NOS, but at higher concentrations; the IC₅₀ values for rat nNOS and bovine eNOS are 34 and 150 nM, respectively.

Synonyms: (5Z)-2-Amino-5-[(4-aminophenyl)methylene]-4(5H)-thiazolone; 5-(4-Aminobenzylidene)-2-iminothiazolidin-4-one Molecular Formula: C10H9N3OS Molecular Weight: 219.26 Linear Structural Formula: C10H9N3OS Purity: >=98% (HPLC) Storage: 2-8C Biochem Physiol Actions: PFM39…

A protopanaxadiol that has diverse in vitro and in vivo effects, including cardioprotective, neuroprotective, and anti-inflammatory actions.

A selective inhibitor of human collagenase-3, also known as MMP-13, producing 89% inhibition at 10 µg/ml; used to evaluate the role of MMP-13 in diverse processes.

A non-cholestatic regioisomer of E217G that acts as a substrate for MRP2, competing with E217G for MRP2-mediated transport (IC₅₀ = 14.2 µM).

A cell-permeable derivative of 2-HG.

A selective inhibitor of the mouse carboxylesterases Ces3 and Ces 1f (IC₅₀ = ~0.1 µM); corrects multiple features of metabolic syndrome in obese-diabetic db/db mice and in mice with diet-induced obesity; also inhibits hCES1, the human ortholog of mouse Ces3 (IC₅₀ = ~50 nM).

A symmetric bis-glycolamide that inhibits the eIF2α phosphorylation-mediated unfolded protein response (IC₅₀ = 5 nM in a cell-reporter assay); passes through the blood-brain barrier and significantly enhances learning and memory in mice and rats.