50 mg, 314245-33-5
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IU1
Cayman ChemicalA reversible, small molecule inhibitor of USP14 deubiquitination (IC50 = 4-5 μM); stimulates ubiquitin-dependent protein degradation in vitro (34 μM) and in cells (50 μM); reduces accumulation of oxidized proteins in HEK293 cells, alleviating cytotoxicity induced by oxidative stress.
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