MilliporeSigma, Supplies, 10 µg
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SILu(TM) Prot Insulin is a recombinant, stable 15N isotope-labeled human Insulin Expressed in P. pastoris, it is designed to be used as an internal standard for bioanalysis of Insulin in mass-spectrometry. SILu(TM) Prot Insulin is a disulfate bonded hetero-dimer protein composed of two chains.…
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PIP5K3 (PIKFYVE), Active PRECISIO(R) Kinase, recombinant
MilliporeSigmaPurity: 70-95% (SDS-PAGE) Storage: -70C Application: Useful for kinase assay. Biochem Physiol Actions: Recombinant human PIP5K3 (1400-end) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. PIP5K3 (also known as phosphatidylinositol-3-phosphate 5-kinase type…
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MDL No.: MFCD02685750 Purity: >=95% (SDS-PAGE) Storage: -20C UNSPSC Code: 12352200 Biochem/physiol Actions: Activin-A participates in a diverse array of functions that include; hypothalamic/pituitary/gonadal hormone secretion, insulin secretion; cell growth, differentiation and survival…
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Synonym(s): IL-2; hIL-2; Interleukin-2; T-cell growth factor Physical form: Lyophilized, 0.2 μm filtered, no additives. Analysis Note: The biological activity is measured by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells. Storage: −20°C
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SILu(TM) Prot VEGF165 is a recombinant, stable isotope-labeled human VEGF165 which incorporates [13C6,15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in human 293 cells, it is designed to be used as an internal standard for bioanalysis of VEGF165 by mass-spectrometry.Suggested Quantitative…
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Programmed cell death 1 ligand 1 (PD-L1), which is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules. PD-L1 is a cell surface immunoglobulin with two Ig-like domains within the extracellular region and a short…
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Synonym(s): SDF-1α; SDF1 Purity: ≥97% (SDS-PAGE) Storage: −20°C
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PP2A ALPHA/PPP2R1A Complex, Active recombinant
MilliporeSigmaPurity: 70-95% (SDS-PAGE) Storage: -70C Application: Useful for Phosphatase assay and Western blot. Biochem Physiol Actions: Recombinant full length human PP2Aalpha and human PPP2R1A were expressed by Baculovirus in Sf9 insect cells using an N-terminal His tag. PP2Aalpha is also known…
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Purity: ≥95% (SDS-PAGE) Analysis Note: The specific activity was determined by the dose-dependent proliferation of WISH (heteroploid human amnion cell line) in presence of VSV (vesicular stomatitis virus). Preparation Note: HumanKine IFNα-2A, expressed in human HEK 293 cells, is a…
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ApoA-1 (apolipoprotein A-1) is a 29.0kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. BP- ApoA-1 (apolipoprotein A-1), which is found exclusively in HDL (high-density lipoprotein), has a unique ability…
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SILu(TM)Prot IGF-1 is a recombinant, stable 15N isotope-labeled human IGF-1. Expressed in E. coli, it is designed to be used as an internal standard for bioanalysis of IGF-1 in mass-spectrometry. SILu(TM)Prot IGF-1 is a protein of 70 amino acids, with a calculated molecular mass of 7.74 kDa. …
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Synonyms: FAAR; MGC3931; NR1C2; NUC1; NUCI; NUCII; PPARB Purity: >=70% (SDS-PAGE) Storage: -70C UNSPSC Code: 12352200 Biochem/physiol Actions: There is evidence that a group of closely related nuclear receptors, called peroxisome proliferator-activated receptors (PPARs), may be involved…
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Synonym(s): KAT3B; RP1-85F18.1; RSTS2; p300 Purity: ≥80% (SDS-PAGE) Storage: −70°C
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Purity: >=70% (SDS-PAGE) Activity: activity: 259-351 nmol/min·mg Storage: -70C UNSPSC Code: 12352200 Application: PIM2, active, GST tagged human has been used for in vitro kinase assay in study of PIM kinases role in fms-like tyrosine kinase 3 inhibitors (FLT3i)-resistant acute myeloid…
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Synonyms: MGC57564; PKC-gamma; PKCC; PKCG; PRK CG; SCA14 MDL No.: MFCD00241716 Purity: >=70% (SDS-PAGE) Activity: activity: 435-589 nmol/min·mg Storage: -70C UNSPSC Code: 12352200 General description: PKCγ (protein kinase C γ) is a s a serine/threonine kinase belonging to the…
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SILu(TM)Prot IFNG Interferon Gamma human recombinant
MilliporeSigmaInterferon gamma (IFNgamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFNgamma is secreted by T helper cells (specifically, Th1 cells), cytotoxic T cells (TC cells) and Natural killer (NK) cells. When combined with other inflammatory cytokines,…
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Synonyms: CADTK; CAKB; FADK2; FAK2; PKB; PTK; PTK2B; RAFTK Purity: >=70% (SDS-PAGE) Activity: activity: 216-292 nmol/min·mg Storage: -70C UNSPSC Code: 12352200 General description: PYK2 (proline-rich tyrosine kinase 2, also known as FAK2/RAFTK) belongs to the focal adhesion PTK…
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Purity: ≥95% (SDS-PAGE) Application: Cystatin C is an inhibitor of cysteine proteases including cathepsin B (which has been identified as the most important β-amyloid-degrading enzyme. Measurement of cystatin C in serum is replacing creatinine as an indicator of kidney function…
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Synonym(s): TNF-α CAS No.: 94948-59-1 Purity: ≥95% (SDS-PAGE) Analysis Note: The specific activity was determined by the dose-dependent cytotoxity of the TNF alpha sensitive cell line L-929 in the presence of actinomycin D. Preparation Note: HumanKine TNF-α is expressed…
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Synonym(s): IL-3; mIL-3; Interleukin-3 from mouse Purity: ≥98% (SDS-PAGE and HPLC) Physical form: Lyophilized with 0.5 mg of bovine serum albumin. Sterile filtered through a 0.2 μm filter. Analysis Note: The biological activity is measured by the dose-dependent stimulation of…
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Synonyms: Gelantinase-B; Gelatinase, 95 kDa; MMP-9 MDL No.: MFCD01323840 Purity: >95% (SDS-PAGE) Storage: -70C UNSPSC Code: 12352204 Biochem/physiol Actions: MMP-9 degrades the collagens that make up the extracellular matrix, which has a role in the control of angiogenesis. …
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Synonyms: Cancer-associated PSA; PSA MDL No.: MFCD00165544 Storage: -20C UNSPSC Code: 12352200 General description: Prostate specific antigen (PSA) is a 26kDa single-chain glycoprotein containing 237 amino acids, encoded by the kallikrein gene mapped to human chromosome 19. It is…
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CAS Number: 9007-49-2 MDL No.: MFCD00166896 Storage: -20C UNSPSC Code: 41105600 General description: The pUC19 plasmid (2,686 bp) confers ampicillin resistance and complement defects in beta-galactosidase in appropriate host strains. The multiple cloning site (MCS) is within the…
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Synonyms: MGC126514; MGC141919; PRKCQ; PRKCT; nPKC-theta Purity: >=70% (SDS-PAGE) Activity: activity: 673-911 nmol/min·mg Storage: -70C UNSPSC Code: 12352200 General description: PKCθ (protein kinase C θ) is a serine/threonine kinase, belonging to protein kinase C family. …
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Synonym(s): Cachectin; TNF-α Purity: ≥98% (SDS-PAGE and HPLC) Physical form: Lyophilized from an 0.2 μm-filtered buffered solution with bovine serum albumin as a carrier. Analysis Note: The biological activity is measured in a cytotoxic assay using a TNF-susceptible mouse…
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Synonym(s): PGF-2; PlGF-2 MDL Number: MFCD03458038 Purity: >97% (SDS-PAGE) Storage: −20°C
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Synonym(s): SCF; c- Kit ligand Purity: >97% (SDS-PAGE) Physical form: Lyophilized from a 0.2 μm filtered solution in PBS containg 50 μg BSA /μg cytokine. Analysis Note: The proliferative activity is tested in culture using TF-1 cells or by the dose dependent…
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Synonyms: MGC48865 Purity: >=70% (SDS-PAGE) Activity: activity: 1626-2201 nmol/min·mg Storage: -70C UNSPSC Code: 12352200 Biochem/physiol Actions: Protein kinase A (PKA) is a mediator of cAMP (cyclic adenosine monophosphate) and contains two regulatory and two catalytic subunits.…
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pT7-FLAG(TM)-2 Expression Vector,
MilliporeSigmaStorage: -20C UNSPSC Code: 12352200 General description: pT7-FLAG-2 is a 4.8 kb E . coli expression vector used for cloning and cytoplasmic expression of a properly inserted open reading frame as a C-terminal FLAG(R) fusion protein containing the FLAG epitope (DYKDDDDK). The promoter region…
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SILu(TM)Prot ALB is a recombinant, stable isotope-labeled human albumin which incorporates [13C6, 15N4]-Arginine and [13C6, 15N2]-Lysine. Expressed in human 293 cells, it is designed to be used as an internal standard for bioanalysis of albumin in mass-spectrometry. SILu(TM)Prot ALB is a monomer of…
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Serpin A1 also known as alpha-1-antitrypsin (A1AT), serum trypsin inhibitor, alpha-1 proteinase inhibitor (A1PI), AAT, which belongs to the serpin family. Most serpins inactivate enzymes by binding to them covalently, requiring very high levels to perform their function. Like all serine protease…
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Synonyms: PDPK1; PRO0461 Purity: >=70% (SDS-PAGE) Activity: activity: 102-138 nmol/min·mg Storage: -70C UNSPSC Code: 12352200 Biochem/physiol Actions: PDPK1 (3-phosphoinositide dependent protein kinase 1) is a serine/threonine protein kinase which is activated upon accumulation of…