Synonyms: MGC48865
Purity: >=70% (SDS-PAGE)
Activity: activity: 1626-2201 nmol/min·mg
Storage: -70C
UNSPSC Code: 12352200
Biochem/physiol Actions: Protein kinase A (PKA) is a mediator of cAMP (cyclic adenosine monophosphate) and contains two regulatory and two catalytic subunits. Mutations in PRKACA (protein kinase cAMP-activated catalytic subunit α) are associated with Cushing′s syndrome. PRKACA encodes two splice variants, Cα1 and Cα2. Cα1 is widely expressed and Cα2 is restricted to the sperm cells.
Physical form: Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.