LKT Labs
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4-Bromoflavone
LKT Labs4-Bromoflavone displays antioxidative and chemopreventive activities. 4-Bromoflavone activates Nrf2-Keap1-ARE complex signaling and also induces quinone reductase and other phase II enzymes. Additionally, this compound prevents the development of mammary tumors, increasing tumor latency in vivo.
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Berberine Chloride
LKT LabsBerberine is an isoquinoline alkaloid found in a variety of plants, including barberry, goldenseal, Oregon grape, California poppy, and the Amur cork tree. Berberine fluoresces under ultraviolet light and is often used to stain heparin in mast cells. Berberine displays many beneficial effects,…
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Acivicin
LKT LabsAcivicin is a fermentation product of Streptomyces; it is a glutamine analog. Acivicin inhibits ?-glutamyl transferase, CTP synthetase, GMP synthetase, and FGAM synthetase, preventing purine synthesis. Acivicin exhibits anticancer and antifungal activity, although its potential chemotherapeutic…
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Aspartame
LKT LabsAspartame is a dipeptide ester that is used as an artificial sweetener in commercial food production. Aspartame exhibits antibacterial efficacy against Porphyromonas, a periodontal pathogen. In vivo, aspartame also displays antinociceptive activity, increasing latency times in tail flick and paw…
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ß-Cembrenediol Methyl Ether
LKT Labsβ-cembrenediol is a diterpene product found in tobacco plants and cigarette smoke. β-cembrenediol displays weak anticancer and antimicrobial activity, exhibiting some cytotoxicity in cellular models. Grade: ≥98%
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Altretamine
LKT LabsAltretamine is an anticancer chemotherapeutic agent that binds DNA at guanine and cytosine residues, forming DNA adducts. This alkylating agent is also metabolized to formaldehyde. Altretamine is clinically used to treat ovarian cancer.
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Calcitonin gene-related peptide (CGRP) is an endogenous neuropeptide that exhibits anti-inflammatory, anti-resorptive, anxiogenic, neuroprotective, and pro-angiogenic activities. In animal models of livery injury, CGRP displays protective benefit, decreasing pro-inflammatory cytokine levels. CGRP…
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Carbamazepine
LKT LabsCarbamazepine is an antiepileptic/anticonvulsant that also exhibits antipsychotic and anti-inflammatory activities. Carbamazepine inhibits voltage-gated Na+ channels, stabilizing the inactive conformation of the channel. Carbamazepine also potentiates GABA receptor signaling and inhibits…
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Bongkrekic Acid
LKT LabsBongkrekic acid is an antioxidative compound that inhibits mitochondrial respiration by preventing the mitochondrial permeability transition (MPT); it suppresses transport of ADP/ATP across the mitochondrial inner membrane, decreasing oxidative stress. Grade: ≥98%
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ß-Cembrenediol
LKT LabsCembrenediols are diterpenes originally found in Anisomeles. These compounds exhibit antibacterial activity against Mycobacterium and antifungal activity against Colletotrichum. Grade: ≥98%
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Chondroitin Sulfate, cow
LKT LabsChondroitin sulfate (CS) is a polyanionic sulfated glycosaminoglycan that displays anti-arthritic, antioxidative, and anti-inflammatory activities. CS is an endogenous component of the extracellular matrix of connective tissues and is responsible for their resistance and elasticity. CS is often…
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3-tert-Butyl-5-Methoxycatechol
LKT Labs3-Tert-butyl-5-methoxy-catechol exhibits anticancer activity, inhibiting proliferation of leukemia cells. This compound may also induce cellular differentiation in vitro.
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CH5132799
LKT LabsCH5132799 is an inhibitor of PI3K that is somewhat selective for p110a isoforms. This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in breast cancer, ovarian cancer, prostate cancer, and endometrial cancer models.
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Bleomycin A5 Hydrochloride
LKT LabsBleomycin A5 is an anticancer chemotherapeutic that binds DNA and induces DNA cleavage and strand breaks; it is highly toxic. Bleomycin is clinically used to treat lymphomas, squamous cell carcinomas, and testicular cancer. Additionally, this compound induces apoptosis, alters cell cycle…
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Butylated Hydroxytoluene
LKT LabsButylated hydroxytoluene (BHT) is commonly used as a food and cosmetics additive; it exhibits antioxidative and anti-inflammatory activities. BHT may also display neuroprotective benefit, decreasing ethanol-induced brain damage and neurodegeneration and suppressing activation of NF-?B activation…
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L-(+)-Ascorbic Acid
LKT LabsL-Ascorbic acid is a vitamin C compound that can be found in many food and plant sources. L-Ascorbic acid exhibits antioxidative benefit and reducing activity; in vitro, it can act as a prolyl hydroxylase cofactor. Grade; ≥98%
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Adenine
LKT LabsAdenine is a purine nucleotide base that is involved in the synthesis of RNA and DNA. Adenine also plays roles in cellular respiration as a component of ATP, NAD, and FAD. Grade: ≥98%
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AGDV
LKT LabsAGDV is a C-terminal peptide sequence found on fibrinogen that is known as a binding site for glycoprotein IIb/IIIa (integrin aIIbß3); this binding is required for platelet adhesion and aggregation.
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Carcinoembryonic Antigen (605-613)
LKT LabsThis peptide is an epitope of carcinoembryonic antigen and is recognized by T cells in the immune system; it may have potential in the development of vaccines or targeting therapies. Grade: ≥95%
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N-Acetyl-S-(N’-phenylthiocarbamoyl)-L-cysteine (PITC) is a cysteine conjugate of N-acetyl-phenylisothiocyanate. Isothiocyanates are typically found in plants of the Brassicaceae family, including broccoli, cabbage, and radish. Isothiocyanates are best known for their antioxidative, anticancer…
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Ceftriaxone Sodium
LKT LabsCeftriaxone is a third generation β-lactam cephalosporin antibiotic. Ceftriaxone exhibits antibacterial efficacy against gram positive and gram negative bacteria, inhibiting penicillin binding protein activity to prevent peptidoglycan synthesis and bacterial cell wall formation. Ceftriaxone is…
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L-Carnitine Tartrate
LKT LabsL-Carnitine is an endogenous quaternary ammonium compound required for fatty acid transport; it is often given as a dietary supplement. The L-isomer is active, exhibiting anti-osteoporotic, antioxidative, and cardioprotective activities. In a clinical setting, L-carnitine administration increases…
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Acetylsalicylic Acid
LKT LabsNSAID and COX-1/2 inhibitor used to decrease inflammation. It inhibits platelet aggregation and prolongs bleeding time by decreasing levels of thromboxane A2. Chronic administration decreases risk of cancer and cardiovascular events.
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Aflatoxin B2
LKT LabsAflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin B2 is cytotoxic; it inhibits DNA synthesis and induces cell cycle arrest.
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Bromhexine Hydrochloride
LKT LabsBromhexine is a synthetic derivative of vasicine that exhibits mucolytic and antioxidative activities. Bromhexine increases production of serous mucus, decreases mucus viscosity, and helps cilia transport mucus out of the lungs. Bromhexine is clinically used to treat respiratory disorders…
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Ceftiofur Hydrochloride
LKT LabsCeftiofur is a third generation β-lactam antibacterial used in livestock. Like other similar antibiotics, ceftiofur inhibits synthesis of bacterial cell walls by inhibiting penicillin binding proteins. Ceftiofur also displays anti-inflammatory activity. In vivo, this compound decreases…
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Capsaicin, natural
LKT LabsCapsaicin is an agonist of transient receptor potential vanilloid (TRPV) channels that was originally found in peppers of the Capsicum genus. Capsaicin exhibits analgesic, anti-inflammatory, anti-obesity, and anticancer chemotherapeutic activity. Capsaicin also displays bronchoconstrictive activity…
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Brevetoxin 2
LKT LabsBrevetoxins are lipid-soluble polyether neurotoxins initially produced by the dinoflagellate Karenia brevis. Brevetoxins act as agonists, binding the neurotoxin site 5 on SCN4A/Nav1.4 and SCN5A/Nav1.5 voltage-gated Na+ channels in skeletal muscle and cardiac tissue, producing a channel opening…
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Citalopram Hydrobromide
LKT LabsCitalopram is a selective serotonin reuptake inhibitor (SSRI) that inhibits the serotonin transporter (SERT); citalopram is clinically used for its antidepressant and anxiolytic activities, although it may prolong the QT interval. The S-isomer of citalopram is active and is sold on its own as…
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[Val5]-Angiotensin II, Human
LKT LabsAngiotensin II (AT II) is a peptide produced from AT I by angiotensin-converting-enzyme (ACE). AT II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels; this results in contraction and vasoconstriction, increasing blood…
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Citrinin
LKT LabsCitrinin is a mycotoxin initially produced by Penicillum, Aspergillus, and Monascus. Citrinin exhibits cytotoxic, cardiotoxic, nephrotoxic, and pro-oxidative activities. In leydig cells, citrinin inhibits testosterone production and induces caspase-mediated apoptosis. In embryos, citrinin alters…
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ALAL
LKT LabsALAL is a peptide sequence commonly used as a linker to conjugate compounds together to better target delivery of anticancer chemotherapeutics. Grade: ≥95%