LKT Labs

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  • Blasticidin S Hydrochloride

    LKT Labs

    Blasticidin S is an antibiotic that also exhibits anti-parasitic activity. Blasticidin S inhibits protein synthesis by inducing deformations in P-site tRNA. Blasticidin S inhibits aflatoxin production in species of Aspergillus.

  • Amoxicillin

    LKT Labs

    Amoxicillin is a ß-lactam penicillin antibiotic that exhibits antibacterial efficacy against both gram positive and gram negative bacteria. Amoxicillin inhibits peptidoglycan polymerization through binding of penicillin binding proteins, inhibiting cell wall synthesis.

  • Amsacrine

    LKT Labs

    Amsacrine is an anticancer chemotherapeutic acridine derivative that is clinically used to treat acute myelogenous leukemia (AML). Amsacrine acts as a DNA intercalator, binding AT base pairs; this inhibits the activity of topoisomerase II, preventing DNA repair. In leukemia cells, amsacrine…

  • Ciprofloxacin

    LKT Labs

    Ciprofloxacin is a second generation fluoroquinolone antibiotic that exhibits antibacterial activity against both gram negative and gram positive bacteria. Ciprofloxacin inhibits DNA gyrase and topoisomerase IV, preventing DNA replication.

  • Camptothecin

    LKT Labs

    Camptothecin is a quinolone alkaloid precursor of irinotecan; it is originally produced by Camptotheca. Camptothecin exhibits anticancer chemotherapeutic activity, inhibiting topoisomerase I and inducing double-stranded DNA breaks. Camptothecin is extremely cytotoxic and only its derivatives are…

  • Aristolochic Acid A

    LKT Labs

    Aristolochic acid A is a carcinogenic compound found in Aristolochia and Radix that has commonly been used in traditional Chinese medicine. This compound inhibits phospholipase A2 (PLA2) and decreases GABA-induced release of arachidonic acid and phosphatidylcholine as well as exocytosis in vitro.

  • Alamethicin

    LKT Labs

    Alamethicin is a peptabiol peptide initially produced by species of Trichoderma. Alamethicin is an antimicrobial peptide (AMP) that disturbs the lipid layer of the cell membrane, aggregating and forming pores and causing cell lysis. Grade: ≥95%

  • Capecitabine

    LKT Labs

    Capecitabine is an antifolate anticancer chemotherapeutic that acts as a prodrug of 5-fluorouracil (5-FU), a fluoropyrimidine carbamate that inhibits thymidylate synthase. Capecitabine is converted to 5-FU by thymidine phosphorylase in vivo. Capecitabine displays varying efficacy in the treatment…

  • Adrenocorticotropic Hormone (1-14)

    LKT Labs

    Adrenocorticotropic hormone (ACTH) is a peptide derived from proopiomelanocortin (POMC) processed and secreted in the pituitary gland. ACTH binds and activates melanocortin-2 (MC2) receptors, stimulating cortisol production in the adrenal cortex. ACTH exhibits anti-inflammatory and immunomodulatory…

  • Bradykinin Potentiator C

    LKT Labs

    This peptide is secreted by Agkistrodon vipers and inhibits activity of angiotensin-converting enzyme (ACE) and bradykinin inhibiting peptidases. Grade: ≥95%

  • Aflatoxin G2

    LKT Labs

    Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin G2 is cytotoxic; it inhibits DNA synthesis and induces cell cycle arrest.

  • AG-1024

    LKT Labs

    AG-1024 is a tyrphostin that inhibits IGF-1R, exhibiting anticancer chemotherapeutic activity. In hepatocellular carcinoma cells and breast cancer cells, AG-1024 increases levels of cytochrome C, decreases activation of ERK, and inhibits invasion and p

  • Bleomycin Sulfate

    LKT Labs

    This product is a mixture of bleomycin sulfate salts; bleomycin A2 is pictured. Bleomycin is an anticancer chemotherapeutic that binds DNA and induces DNA cleavage and strand breaks; it is highly toxic. Bleomycin A5 is clinically used to treat lymphomas, squamous cell carcinomas, and testicular…

  • Cerulenin

    LKT Labs

    Cerulenin is an inhibitor of fatty acid synthase found in Cephalosporium. Cerulenin exhibits antibiotic, antifungal, and anticancer chemotherapeutic activities. In cellular and animal models of colon cancer, cerulenin induces apoptosis and cellular death and decreases tumor growth. Cerulenin may…

  • Adrenorphin

    LKT Labs

    Adrenorphin is an endogenous opioid peptide produced from cleavage of proenkephalin A. Adrenorphin acts as an agonist at ?-opioid receptors (?ORs) and µ-opioid receptors (µORs). Like other opioids, adrenorphin exhibits analgesic, antinociceptive, and gastrointestinal motility modulating…

  • [Des-Arg9]-Bradykinin

    LKT Labs

    Bradykinin is a peptide that exhibits natriuretic, antioxidative, vasodilatory, and pro-angiogenic activities. Bradykinin stimulates bradykinin receptors and increases PLC activity, decreasing ENaC open probability, inhibiting distal nephron Na+ transport, and inducing natriuresis. In vitro,…

  • Ceftiofur Hydrochloride

    LKT Labs

    Ceftiofur is a third generation β-lactam antibacterial used in livestock. Like other similar antibiotics, ceftiofur inhibits synthesis of bacterial cell walls by inhibiting penicillin binding proteins. Ceftiofur also displays anti-inflammatory activity. In vivo, this compound decreases…

  • Bombesin

    LKT Labs

    Bombesin is a gastrin-releasing peptide (GRP) analog that stimulates intestinal function; it was originally found in Bombina toads and binds bombesin receptors (BBRs) and GRP receptors. Mammalian homologs of this compound are neuromedin B and GRP. Bombesin exhibits antiepileptic/anticonvulsant…

  • Butyric Acid Sodium

    LKT Labs

    Sodium butyrate is an inhibitor of histone deacetylases (HDACs) that exhibits antidepressant, immunomodulatory, and anticancer activities. In animals undergoing the light dark test, tail suspension test, and forced swim test, sodium butyrate decreases restraint stress-induced depression. In…

  • AS-604850

    LKT Labs

    AS-604850 is an inhibitor of p110γ PI3K that exhibits anti-inflammatory and immunosuppressive activities. In animal models of experimental autoimmune encephalitis (EAE), AS-604850 decreases the number of leukocytes infiltrated into the CNS and ameliorates disease symptoms. AS-604850 also…

  • L-Alaninol

    LKT Labs

    L-Alaninol is an amino acid alcohol that exhibits anticancer activity. L-Alaninol inhibits proliferation of melanoma cells and increases levels of cytochrome c reductase and tau-glutamyl transpeptidase. Grade: ≥98%

  • BEZ235

    LKT Labs

    BEZ235 inhibits PI3K and mTORC1/2, exhibiting anticancer chemotherapeutic activity. In nasopharyngeal cancer cells, BEZ235 induces G1 phase cell cycle arrest and apoptosis; in similar animal models of nasopharyngeal or cholangiocarcinoma, this compound inhibits tumor growth. BEZ235 also induces…

  • Aprepitant

    LKT Labs

    Aprepitant is an inhibitor of the tachykinin/neurokinin 1 (NK1) receptor that acts as an antiemetic or anti-nausea medicine. Aprepitant also exhibits some anticancer chemotherapeutic and anti-angiogenic benefit through its inhibition of NK1 receptors, preventing binding of substance P and…

  • Borrelidin

    LKT Labs

    Borrelidin is a macrolide antibiotic initially produced by Streptomyces. Borrelidin exhibits anti-parasitic, antifungal, anticancer, and anti-angiogenic activities. This compound inhibits threonyl-tRNA synthetase/ligase, inhibiting growth and survival of Trypanosoma, Plasmodium, and Phytophthora.…

  • Aphidicolin

    LKT Labs

    Aphidicolin is a diterpene antibiotic initially produced by Cephalosporum that exhibits antiviral activities. Aphidicolin inhibits eukaryotic DNA replication by inhibiting DNA polymerase and inducing S phase cell cycle arrest. In research models, aphidicolin is used to study cell cycle phases. This…

  • Alfuzosin Hydrochloride

    LKT Labs

    Alfuzosin is an a1-adrenergic receptor antagonist that is used clinically to treat benign prostatic hyperplasia (BPH); it relaxes prostatic smooth muscle and increases the urinary flow rate. Alfuzosin also delays cardiac repolarization by increasing the Na+ current. This compound prolongs action…

  • 4-Aminosalicylic Acid

    LKT Labs

    4-Aminosalicylic acid exhibits anti-inflammatory, antioxidative, and antibacterial activities; it is clinically used to treat inflammatory bowel disease (IBD), Crohn’s disease, and colitis, as it acts primarily in the colon. 4-Aminosalicylic acid is used against Mycobacterium as a treatment for…

  • Brain Injury-derived Neurotrophic Peptide (3)

    LKT Labs

    This peptide supports neuronal survival and protects neurons in glutamate-induced cell death assays.

  • Ampiroxicam

    LKT Labs

    Ampiroxicam is a non-steroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory and analgesic activities; it inhibits COX-1 and COX-2. Ampiroxicam is a prodrug of piroxicam that does not inhibit prostaglandin synthesis itself. In animal models of inflammation, ampiroxicam decreases…

  • Arformoterol Tartrate

    LKT Labs

    Arformoterol is the R,R enantiomer of formoterol. Arformoterol exhibits anti-inflammatory and anti-asthma activities, potentiating the effects of co-administered glucocorticoids in the treatment of asthma and chronic obstructive pulmonary disorder (COPD). Arformoterol activates β2-adrenergic…

  • Acemetacin

    LKT Labs

    Prodrug of indomethacin, NSAID, and COX-1/2 inhibitor used to treat pain and arthritis. It also scavenges ROS and RNS.

  • Aflatoxin B1

    LKT Labs

    Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin B1 is the most cytotoxic of all aflatoxins; it inhibits DNA synthesis and induces cell cycle arrest.

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