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  • Aconitine

    LKT Labs

    Aconitine is a toxin found in Aconitum that exhibits antipyretic, antihypertensive, analgesic, and antinociceptive activities. Aconitine binds neurotoxin binding site 2 of Na+ channels, forcing the channel to stay open longer, allowing continual depolarization, Na+ influx, and eventually paralysis.…

  • N-Acetyl-L-Cysteine

    LKT Labs

    N-Acetyl-L-cysteine exhibits antioxidative, mucolytic, anti-inflammatory, antiviral, antipsychotic, and neuromodulatory activities. N-Acetyl-L-cysteine has clinically been used to treat acetaminophen overdose; it is occasionally commercially sold as a supplement. N-Acetyl-L-cysteine acts as a…

  • Baicalin

    LKT Labs

    Baicalin is a flavone found in Scutellaria that exhibits antiviral, antioxidative, antihypertensive, cardioprotective, anti-inflammatory, and anticancer chemotherapeutic activities. Baicalin inhibits prolyl oligopeptidase. Baicalin also inhibits neuraminidase, preventing influenza infection. In…

  • Butylated Hydroxytoluene

    LKT Labs

    Butylated hydroxytoluene (BHT) is commonly used as a food and cosmetics additive; it exhibits antioxidative and anti-inflammatory activities. BHT may also display neuroprotective benefit, decreasing ethanol-induced brain damage and neurodegeneration and suppressing activation of NF-?B activation…

  • Carvedilol Phosphate Hemihydrate

    LKT Labs

    Carvedilol phosphate is a cardioprotective a1- and ß1/2-adrenergic receptor inhibitor used to treat congestive heart failure; its inhibitory action at adrenergic receptors slows heart rhythm, decreasing force, pressure, and cardiac workload. Carvedilol phosphate also inhibits release of…

  • 3'-Azido-3'-deoxythymidine

    LKT Labs

    AZT is a thymidine nucleoside analog that inhibits reverse transcriptase and is clinically used to treat HIV/AIDS. AZT inhibits viral DNA synthesis, preventing viral replication; at high doses, it may inhibit DNA polymerase. Use of AZT is often limited

  • S-(-)-Carbidopa Monohydrate

    LKT Labs

    S-(-)-Carbidopa is a hydrazine that inhibits L-amino acid decarboxylase; it only acts peripherally when given systemically, as it does not cross the blood-brain barrier. S-(-)-Carbidopa inhibits formation of dopamine granules and dopamine-mediated swimming activity in sea urchins. In animal models…

  • Cisplatin

    LKT Labs

    Cisplatin is a platinum-based cross-linking agent that exhibits anticancer chemotherapeutic activity. Cisplatin induces crosslinks between guanine bases on DNA; it is clinically used to treat various forms of cancer. In lung cancer cells, cisplatin decreases phosphorylation of PI3K, Akt, and FOXO3a…

  • Anisodamine

    LKT Labs

    Anisodamine is a tropane alkaloid originally found in plants in the Solanaceae family; it exhibits anti-inflammatory activity and is clinically used to induce atropinization in organophosphate poisoning subjects and to improve acute lung injury pathology and respiratory parameters. Anisodamine…

  • Amphotericin B

    LKT Labs

    Amphotericin B is a polyene antifungal compound that increases levels of ROS and forms pores or channels in membranes by binding membrane sterols. Amphotericin B induces iNOS, activates astrocytes, and increases expression of IL-1ß, TNF-a, BDNF, and GDNF, displaying potential neuroprotective…

  • Aceclofenac

    LKT Labs

    Aceclofenac is a diclofenac analog that exhibits anti-inflammatory and analgesic activities. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that somewhat selectively inhibits COX-2; it is clinically used to treat rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.…

  • Abacavir Sulfate

    LKT Labs

    Guanosine analog and inhibitor of RT, guanylyl cyclase, and telomerase used to treat HIV infection. Grade: ≥98%

  • Bleomycin Sulfate

    LKT Labs

    This product is a mixture of bleomycin sulfate salts; bleomycin A2 is pictured. Bleomycin is an anticancer chemotherapeutic that binds DNA and induces DNA cleavage and strand breaks; it is highly toxic. Bleomycin A5 is clinically used to treat lymphomas, squamous cell carcinomas, and testicular…

  • Alyssin Sulfone

    LKT Labs

    Alyssin sulfone is a sulfone analog of sulforaphane, an isothiocyanate (ITC). Alyssin sulfone exhibits antioxidative and anticancer activity. This compound inhibits the growth of colon cancer cells in vitro and induces phase II enzymes, increasing Nrf2 activity. Grade: ≥97%

  • Artemether

    LKT Labs

    Artemether is a sesquiterpene lactone derived from Artemisia. Artemisinins such as artemether are best known for their antimalarial activity. Artemether exhibits anti-parasitic activity against Plasmodium, Leishmania, and Schistosoma.

  • Chymostatin

    LKT Labs

    Chymostatin is an inhibitor of proteases such as chymase that is used in research models.

  • Dihydroartemisinin

    LKT Labs

    Dihydroartemisinin is a sesquiterpene lactone that can be derived from Artemisia. Dihydroartemisinin exhibits anticancer, antiviral, anti-inflammatory, anti-asthma, and anti-parasitic activities. Artemisinins such as dihydroartemisinin are best known for their antimalarial activity.…

  • 9-Aminocamptothecin

    LKT Labs

    9-amino-Camptothecin is a camptothecin derivative. Camptothecin is a quinolone alkaloid precursor of irinotecan; it is originally found in Camptotheca. Camptothecin exhibits anticancer chemotherapeutic activity, inhibiting topoisomerase I and inducing double-stranded DNA breaks. Camptothecin is…

  • Bis(3,5-dibromosalicyl) Succinate

    LKT Labs

    Bis(3,5-dibromosalicyl) succinate is an aspirin analog that is used to induce hemoglobin chain crosslinks at lysine residues. This compound is used to study hemoglobin function in research models and may be used to develop treatments for sickle-cell anemia. This compound may exhibit…

  • Atropine

    LKT Labs

    Atropine is a tropane alkaloid found in plants in the Solanaceae family. Atropine is an anticholinergic compound that also exhibits analgesic and antinociceptive activities. Atropine is a competitive inhibitor of muscarinic acetylcholine receptors (mAChRs) that is commonly used for ophthalmic…

  • Ascomycin

    LKT Labs

    Ascomycin is an ethyl analog of FK506 that was initially produced by species of Streptomyces. Ascomycin binds FK506 binding protein 12 and the resulting complex inhibits calcineurin/protein phosphatase 2B (PP2B), altering peptidyl-prolyl isomerase activity of the enzyme. Ascomycin exhibits…

  • Bleomycin A5 Hydrochloride

    LKT Labs

    Bleomycin A5 is an anticancer chemotherapeutic that binds DNA and induces DNA cleavage and strand breaks; it is highly toxic. Bleomycin is clinically used to treat lymphomas, squamous cell carcinomas, and testicular cancer. Additionally, this compound induces apoptosis, alters cell cycle…

  • Chlorambucil

    LKT Labs

    Chlorambucil is a nitrogen mustard anticancer chemotherapeutic that acts as an alkylating agent. Chlorambucil is clinically used to treat chronic lymphocytic leukemia (CLL).,

  • L-Citrulline

    LKT Labs

    L-Citrulline is a by product of NO formation from metabolism of L-arginine that exhibits tocolytic and antioxidative activities. L-Citrulline was originally found in watermelon. In isolated rat uteri, L-citrulline decreases uterine contractile force through stimulation of the NO-cGMP relaxant…

  • Cheirolin

    LKT Labs

    Cheirolin is an isothiocyanate (ITC) that exhibits antioxidative activity. Cheirolin is a sulfonyl analog of iberin. Like others ITCs, cheirolin induces phase II enzymes. In vitro, cheirolin increases activation and expression of Nrf2 as well as expression of heme oxygenase 1 (HO-1) and…

  • Biotin

    LKT Labs

    Biotin is a water-soluble B vitamin (vitamin B7) that may be found in many foods but is also administered as a dietary supplement. Biotin is a coenzyme involved in the synthesis of fatty acids, isoleucine, and valine; it also plays a role in gluconeogenesis. Biotin may be found attached to lysine…

  • Bestatin Hydrochloride

    LKT Labs

    Bestatin is a dipeptide inhibitor of aminopeptidases such as aminopeptidase N/CD13. Bestatin displays efficacy in the treatment of lung cancer. This compound exhibits anticancer chemotherapeutic, immunomodulatory, and analgesic activities. Bestatin enhances differentiation of acute promyelocytic…

  • ß-Carotene

    LKT Labs

    ß-Carotene is a red-orange terpene pigment originally found in various plants and fruits; it is a prodrug for vitamin A. ß-Carotene exhibits antioxidative, cytoprotective, anticancer, anti-inflammatory, anti-hyperlipidemic, and anti-obesity activities. ß-Carotene is used in research models to…

  • Cabozantinib

    LKT Labs

    Cabozantanib is an anticancer chemotherapeutic compound that has been approved to treat medullary thyroid cancer and is in clinical trials as a treatment for other types of solid tumors. Cabozantanib exerts its anticancer activity through inhibition of Met, RET, and VEGFR2, increasing apoptosis and…

  • Berteroin

    LKT Labs

    Berteroin is a Erucin homolog that may exhibit antioxidative and anti-androgenic activities. Berteroin is an isothiocyanate (ITC) compound that decreases androgen receptor levels in prostate cancer cells. Berteroin also displays anti-inflammatory properties, decreasing LPS-induced release of…

  • Artesunate

    LKT Labs

    Artesunate is a sesquiterpene lactone derived from Artemisia. Artesunate exhibits anticancer chemotherapeutic, antiviral, anti-angiogenic, and anti-parasitic activities. Artemisinins such as artesunate are best known for their antimalarial activity. Artesunate induces G0/G1 phase cell cycle arrest,…

  • 5-Bromo-2'-Deoxyuridine

    LKT Labs

    5-Bromo-2’-deoxyuridine is a synthetic nucleoside analog of thymidine that is used in research models to label actively proliferating cells. This compound is incorporated into DNA but at low levels does not alter DNA replication. At high levels, this compound displays immunosuppressive activity and…

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