Cayman Chemical, Chemicals, 250 µg
-
Araguspongin B
Cayman ChemicalAn antagonist of the inositol 1,4,5-trisphosphate at its carboxy terminus.
-
8(S)-HETrE
Cayman Chemical8(S)-HETrE is a monohydroxy PUFA produced by rabbit neutrophil lipoxygenase when DGLA is used as a substrate. Although the biological activities of 8(S)-HETrE have not been well characterized, it is expected to behave similarly to 8(S)-HETE.
-
(2S)-Octyl-a-hydroxyglutarate-d17
Cayman ChemicalAn internal standard for the quantification of (2S)-octyl-α-hydroxyglutarate by GC- or LC-MS.
-
17-keto-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
Cayman ChemicalA metabolite of lipoxygenase-mediated oxidation of DPA; activates Nrf2-dependent antioxidant gene expression, acts as a PPARγ agonist (EC50 = ~200 nM), and inhibits pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 µM).
-
(±)8(9)-EET methyl ester
Cayman ChemicalA derivative of (±)8(9)-EET which is stable enough to ship and handle routinely.
-
15(R)-Lipoxin A4
Cayman ChemicalAn aspirin-triggered lipoxin that inhibits LTB4-induced chemotaxis, adherence, and transmigration of the neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.
-
Arachidonic Acid 1,2,3,4,5-13C
Cayman ChemicalAn isotopically enriched form of a PUFA with carbon-13 occurring at positions 1, 2, 3, 4, and 5; used to study metabolic processes related to arachidonic acid by means of mass spectrometry.
-
(±)11-HDHA
Cayman Chemical(±)11-HDHA is an autoxidation product of DHA in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. DHA is metabolized to 11(S)-HDHA by human platelets and canine retina. In addition to 11(S)-HDHA, 14(S)-HDHA is also produced by platelets.…
-
5(S)-HETrE
Cayman Chemical5(S)-HETrE is produced by the action of 5-LO when mead acid is the substrate. There are no literature reports of the biological activity or further metabolic fate of 5(S)-HETrE.
-
T-2 Tetraol
Cayman ChemicalA group A trichothecene mycotoxin derived by the metabolism of T-2 toxin.
-
4-Nitrophenyl ß-D-Cellotrioside
Cayman ChemicalA chromogenic substrate for endoglucanases and cellobiohydrolases.
-
(±)9-HETE
Cayman Chemical(±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC. The racemic HETEs have been quantified as an index of lipid…
-
-
DAF-2 diacetate
Cayman ChemicalDAF-2 diacetate is a sensitive fluorescent indicator for the detection and bioimaging of NO. It is a cell-permeable derivative of DAF-2. Upon entry into the cell, DAF-2 diacetate is transformed into the less cell-permeable DAF-2 by cellular esterases thus preventing loss of signal due to diffusion…
-
Grifolic Acid
Cayman ChemicalA selective partial agonist of GPR120 that induces ERK activation and intracellular calcium responses in mouse enteroendocrine STC-1 cells that express GPR120 endogenously.
-
15-OxoETE
Cayman Chemical15-OxoETE is produced by oxidation of the 15-hydroxyl of 15-HETE. Whether this is a major pathway of 15-HETE metabolism is yet to be clearly established.
-
trans-Resveratrol-d4
Cayman ChemicalAn internal standard for the quantification of trans-resveratrol by GC- or LC-MS.
-
15(R)-HEDE
Cayman Chemical15(R)-HEDE is isolated by the chromatographic resolution of (±)15-HEDE. There are no reports of biological activity associated with 15(R)-HEDE in the literature.
-
(±)15-HETE
Cayman Chemical(±)15-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)15-HETE is similar to that of its constituent enantiomers (Item Nos. 34720 and 34710).
-
Prostaglandin E2-d9
Cayman ChemicalAn internal standard for the quantification of PGE2 by GC- or LC-MS.
-
(±)12-HETE
Cayman Chemical(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers (Item Nos. 34560 and 34570). It aggregates neutrophils with an EC50…
-
(±)11(12)-DHET-d11
Cayman ChemicalAn internal standard for the quantification of (±)11(12)-DHET by GC- or LC-MS.
-
COX-1 Monoclonal FITC Antibody (Clone CX111)
Cayman ChemicalAntigen: purified ovine COX-1 Host: mouse, clone CX111 Cross-Reactivity: (+) ovine, bovine, human, mouse, and rat COX-1, ovine COX-2 (50%), human COX-2 (~5%); (−) mouse COX-2 Application(s): FC and IF Isotype: IgG2b This product is derived by labeling the COX-1 monoclonal…
-
Geranylgeranyl Pyrophosphate (ammonium salt)
Cayman ChemicalAn intermediate in the HMG-CoA reductase pathway derived directly from farnesyl pyrophosphate and used in the biosynthesis of terpenes and terpenoids; also serves as a substrate in the prenylation of a variety of critical intracellular proteins including small GTPases.
-
Atpenin A5
Cayman ChemicalAn antifungal antibiotic that selectively inhibits succinate dehydrogenase (complex II; IC50s = 12 and 3.7 nM in nematode and mammalian mitochondria, respectively, versus IC50s > 100 μM for inhibition of complex I and complex III enzymes); has cardioprotective effects against simulated…
-
Arachidonic Acid methyl ester 1,2,3,4,5-13C
Cayman ChemicalAn isotopically enriched form of a PUFA standard with carbon-13 occurring at positions 1, 2, 3, 4, and 5; used to study metabolic processes related to arachidonic acid by means of mass spectrometry.
-
(±)16-HDHA
Cayman Chemical(±)16-HDHA is an autoxidation product of DHA in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±)16-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant PUFA.
-
(±)20-HDHA
Cayman ChemicalAn autoxidation product of DHA and a potential marker of oxidative stress in brain and retina where DHA is an abundant PUFA.
-
15(S)-HpEDE
Cayman Chemical15(S)-HpEDE is a monohydroperoxy PUFA produced by the action of 15-LO on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Catalog No. 44720).
-
Epoxomicin
Cayman ChemicalA potent anti-tumor agent used as a selective and irreversible inhibitor of the 20S proteasome; inhibits proteasome activity in cell growth assays (IC50 = 4 nM) and demonstrates potent cytotoxicity against B16-F10, HCT116, and Moser solid tumor cells, as well as P388 and K562 leukemia cells (IC50s…
-
Xestospongin C
Cayman ChemicalAn inositol-1,4,5-trisphosphate receptor antagonist; completely blocks the increase in intracellular calcium in vascular smooth muscle cells at a concentration of 25 µM.
-
Harzianopyridone
Cayman ChemicalA natural inhibitor of mitochondrial complex II with antibiotic activities.
![Site Search powered by SLI Systems](http://assets.resultspage.com/logos/sli_logo_2014.png)