Cayman Chemical, 3895-92-9, Biologically Active Small Molecules

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  • Cayman Chemical

    A potent, cell permeable inhibitor of PKC (IC50 = 660 nM); also inhibits BclXL function (IC50 = 1.5 μM), inducing apoptosis in several cancer cell lines; can have PKC-independent effects, activate p38 and JUNK signaling pathways, and induce apoptosis in cancer cells both in vitro and in vivo.