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Cayman Chemical, 13434-13-4, Biologically Active Small Molecules

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Biologically Active Small Molecules 13434-13-4 Cayman Chemical

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Actinonin

Cayman Chemical

A peptidomimetic antibiotic produced by Actinomyces that inhibits aminopeptidases, including MMP-1 (Ki = 300 nM), MMP-2 (IC₅₀ ~ 90 nM), MMP-3 (Ki = 1,700 nM), MMP-7 (IC₅₀ ~ 3,500 nM), MMP-8 (Ki = 130 nM), MMP-9 (Ki = 330 nM), MMP-10 (IC₅₀ ~ 500 nM), MMP-12…

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