Cayman Chemical, Protein, 100 µg
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Thioredoxin 1 Truncated (human recombinant)
Cayman ChemicalSource: one ampoule contains 100 µg of recombinant truncated human thioredoxin
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Formaldehyde Dehydrogenase (P. putida recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tagged protein expressed in E. coli Mr: 44.6 kDa
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PRMT1 (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 69.2 kDa PRMT1 is a class I arginine methyltransferase that methylates arginine residues at a number of glycine and arginine rich regions (GAR motifs) in proteins including histone H4 at arginine 3.
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eIF4E (human recombinant; GST-tagged)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 51.8 kDa
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SIRT6 (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tagged enzyme amino acids 1-355 expressed in E. coli Mr: 43.7 kDa SIRT6 associates specifically with telomeres and functions at chromatin to decrease NF-κB signaling. Mammalian cells depleted of SIRT6 display abnormal telomere structures similar…
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TP53BP1 BRCT domains (human recombinant)
Cayman ChemicalSource: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)
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Hormone-Sensitive Lipase (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tagged protein expressed in Sf21 insect cells MW: 118.3 kDa
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WDR5 (human recombinant)
Cayman ChemicalSource: Recombinant protein expressed in E. coli WDR5 has been demonstrated to bind histone H3 by recognizing the first three amino acids of the N-terminal tail. Binding of WDR5 to a conserved arginine-containing motif in MLL-1, the so-called WDR5 interaction (“Win”) motif, promotes…
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SMN tudor domain (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli MW: 37.9 kDa
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SIRT5 (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged enzyme expressed in E. coli Mr: 60.6 kDa (GST-tag); 26 kDa (native) SIRT5 is located in the mitochondrial matrix and its functions are largely still being elucidated, however a few promising substrates have been studied. SIRT5 has been shown to…
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SIRT3 (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tagged enzyme amino acids 101-399 purified from E. coli Mr: 37 kDa (theoretical); 33.5 kDa (observed) SIRT3, is a mitochondrial protein that is synthesized as an enzymatically inactive protein. Human SIRT3 is activated by a matrix-processing…
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FABP7 (human recombinant)
Cayman ChemicalSource: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli Mr: 19.1 kDa
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Autotaxin (human recombinant)
Cayman ChemicalSource: recombinant C-terminal histidine-tagged protein expressed using a baculovirus overexpression system in Sf21 cells Mr: 98.8 kDa A secreted lysophospholipase D that catalyzes the hydrolysis of LPC to generate LPA; ATX-LPA signaling is involved in a range of pathologies including tumor…
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CBX2 chromodomain (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 38.2 kDa
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JMJD2C tudor domain (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 39.89 kDa
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BRDT bromodomain 2 (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 41.2 kDa BRDT shares homology with the RING3 protein. The two bromodomains of BRDT recognize acetylated histone H4. Loss of BRDT leads to defects in spermatogenesis. In addition to testis specific expression, BRDT was…
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MIF (human recombinant)
Cayman ChemicalSource: Recombinant protein expressed in E. coli MW: 12.6 kDa
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Gcn5 (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 96.3 kDa Recombinant Gcn5 preferentially acetylates lysine 14 on histone H3 in vitro; however, alone it is unable to acetylate nucleosomal core histone substrates. Acetylation of the nucleosomal histones…
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UHRF1 tudor-like region (human recombinant; His-tagged)
Cayman ChemicalSource: Recombinant protein expressed in E. coli Mr: 45.6 kDa
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TP53BP1 tudor-like region (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 42.6 kDa This product contains the tudor domain of TP53BP1. Binding of TP53BP1 to dimethylated lysine 382 on p53 (p53 K382me2), as well as histone H4K20me2, through the tudor domain, has been shown to be important for…
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FABP2 (human recombinant)
Cayman ChemicalSource: recombinant N-terminal His-tagged protein expressed in E. coli Mr: 19.3 kDa
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FABP2 (rat recombinant)
Cayman ChemicalSource: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli Mr: 19.3 kDa Protein concentration: 1.0 mg/ml
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PPARa LBD (human recombinant)
Cayman ChemicalSource: recombinant His-tagged protein purified from E. coli Mr: ~34 kDa PPARα transcriptionally regulates a variety of genes involved in fatty acid metabolism and oxidation, such as acyl-CoA oxidase, enol-CoA hydratase, medium chain fatty acyl-CoA dehydrogenase, fatty acid transport…
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CREB-binding protein bromodomain (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 40.8 kDa CREBBP bromodomain has been shown to modulate the stability and function of the tumor suppressor protein p53. CREBBP bromodomain recognizes the acetylated lysine residue 382 on p53.
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Irisin (human recombinant)
Cayman ChemicalSource: recombinant protein expressed in E. coli. An N-terminal His-tag and SUMOpro tag were removed by cleavage with SUMO protease 1 (Ulp1). Mr: 12.4 kDa
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BRD2 bromodomains 1 and 2 (human recombinant)
Cayman ChemicalSource: Recombinant GST-tagged protein expressed in E. coli Mr: 71.2 kDa The isolated individual or tandem bromodomains of BRD2 have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters.
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SET8 (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tagged protein amino acids 190-352, expressed in E. coli Mr: 21.1 kDa SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and transcriptional activation. SET8 is also a novel…
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PtdIns-(4,5)-P2 Binding Protein
Cayman ChemicalSource: recombinant N-terminal GST-tagged protein purified from E. coli Mr: ~45.2 kDa (18.9 kDa native; 26.3 kDa GST-tagged) PtdIns-(4,5)-P2 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns-(4,5)-P2. PtdIns-(4,5)-P2 can be phosphorylated by…
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PAD4 (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tagged protein expressed in E. coli MW: 75.8 kDa PAD4 is a homodimer that functions as a transcriptional coregulator to catalyze the conversion of specific arginine residues to citrulline in a calcium-dependent manner. PAD4 substrates include histones…
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JMJD2A-Strep tagged (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal Strep II-tagged protein expressed in E. coli Mr: 42.7 kDa JMJD2A catalyzes the demethylation of trimethylated forms of histone at lysine residues 9 and 36. JMJD2A is an α-ketoglutarate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC…
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Serum Retinol Binding Protein 4 (human recombinant)
Cayman ChemicalSource: recombinant His-tagged protein purified from E. coli Mr: ~21 kDa
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BRD4 bromodomain 1 (human recombinant; His-tagged)
Cayman ChemicalSource: Recombinant N-terminal His-tagged protein expressed in E. coli Mr: 16.6 kDa The isolated individual or tandem bromodomains of BRD4 have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters.