Cayman Chemical, 299953-00-7, Chemicals

1 - 1 of 1
Sort
View
Show
  • Cayman Chemical

    An inhibitor of the DNA damage sensor MRN, inhibiting MRN-dependent phosphorylation of histone H2AX (IC50 = 66 μM); prevents activation of ATM by blocking the nuclease activity of Mre11; induces G2 arrest, abolishes the radiation-induced G2/M checkpoint, and prevents homology-directed…