Cayman Chemical, 29066-42-0, Chemicals

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  • Cayman Chemical

    A fungal β-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 μM) by covalently modifying the active Cys129 residue of the enzyme; targets cell walls of pathogens such as S. aureus in a mouse sepsis model of infection.