Cayman Chemical, 1009817-63-3, Chemicals

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  • Cayman Chemical

    An inhibitor of USP14 and UCHL5, two proteasome-associated deubiquitinases; inhibits DUB activity in purified 19S proteasomes with an IC50 value of 2.1 µM; blocks tumor progression in vivo in mice and prevents organ infiltration in mouse models of myeloid leukemia.