Synonym(s): 3-Methyladenine, 6-Amino-3-methylpurine Formula: C6H7N5 Formula weight: 149.15 CAS Number: 5142-23-4 Harmonized Tariff Code:  2933.99

Synonyms: Fmoc-L-ß-HomoAla(4-pyridyl)-OH Fmoc-(S)-3-amino-4-(4-pyridyl)butyric acid Purity Limit: ≥ 99% (HPLC) CAS No.: 270065-69-5 Molecular Formula: C24H22N2O4 Molecular Weight: 402.45 MDL No.: MFCD01861059 Appearance: White powder Melting Point: 172-178ºC Optical…

A natural sesquiterpene lactone that reduces growth (EC₅₀ = 3-35 μM) and induces apoptosis in assorted cancer cell lines; inhibits the activation of Akt (15 μM) in endometriotic epithelial cells and STAT3 activation in THP-1 cells (EC₅₀ = 10 μM); inhibits telomerase…

Synonym(s): (4-Benzyl-piperazin-1-yl)-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-ylmethylene)-amine Empirical Formula: C₂₃H₂₇N₅ Linear Formula: C₂₃H₂₇N₅ Formula Weight: 373.49 MDL Number: MFCD01827306 Purity: ≥98%…

Synonyms: (R)-8-Fluoro-N-(1-oxo-1-(pyrrolidin-1-yl)-3-(3-(trifluoromethyl)phenyl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide hydrochloride Molecular Formula: C23H25F4N3O3S · HCl Molecular Weight: 535.98 Linear Structural Formula: C23H25F4N3O3S · HCl Purity: >=97%…

A potent inhibitor of PDE5 (IC50 = 1-5 nM) that also blocks the activity of PDE11 (IC50 = 10-33 nM); IC50 values against other isoforms of PDE are in the micromolar range; pharmacokinetics are highlighted by its prolonged duration of effect.

analytical standard Synonym(s): 1-(2-Methoxyphenylazo)-2-naphthol; Oil Red 113 Empirical Formula: C₁₇H₁₄N₂O₂ Formula Weight: 278.31 Linear Formula: C₁₇H₁₄N₂O₂ MDL Number: MFCD00046377 Purity: …

Purity Limit: ≥ 96% (NMR) CAS No.: 878799-20-3 Molecular Formula: C9H20N2O2 Molecular Weight: 188.27 MDL No.: MFCD06804533 Appearance: Light yellow to yellow oil Storage Temperature: Store at 0-8°C

Synonyms: Fmoc-(2S,4R)-?-benzylproline MDL No.: MFCD04115782 Molecular Formula: C27H25NO4 Molecular Weight: 427.5 Optical Rotation: [a]D = -22 ± 2º (C=1 in CHCl3) Purity Limit: 99% (HPLC) Storage Temp: Store at 0-8°C Appearance: White powder

Synonym(s): (6R)-BH₄ Empirical Formula: C₉H₁₅N₅O₃ -+ 2HCl Linear Formula: C₉H₁₅N₅O₃ -+ 2HCl Formula Weight: 314.17 MDL Number: MFCD00891665 Storage: −20°C

Elastase is an enzyme from the class of proteases (peptidases) that break down proteins. It hydrolyzes peptide bonds, especially those adjacent to neutral amino acids. Hydrolyses elastin Digests hemoglobin, casein, and fibrin One unit will solublize 1 mg of elastin in 20 minutes at…

A TZD that increases the sensitivity of cells to insulin, stimulating insulin-induced PI3K activity at submicromolar concentrations; increases insulin effectiveness in obese NIDDM subjects; promotes adipocyte differentiation by up-regulating the expression of UCP-2.

Synonyms: N-(3-pyridazinyl)-4-(3-[5-trifluoromethyl-2-pyridinyloxy]benzylidene)piperidine-1-carboxamide; N-3-Pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-1-piperidinecarboxamide; PF-4457845 Molecular Formula: C23H20F3N5O2 Molecular Weight: 455.43 Linear…

Formula: C29H32O13 Formula weight: 588.56 CAS Number: 33419-42-0 Harmonized Tariff Code:  2938.90 Hazard Statements: H350-H302 May cause cancer. Harmful if swallowed. Precautionary Statements: P281-P264-P301+P312-P308+P313-P405-P501a Use personal protective equipment as required.…

MDL No.: MFCD03844607 Molecular Formula: C12H23NO3 Molecular Weight: 229.32 Purity Limit: 99% (GC) Storage Temp: Store at 0-8°C Appearance: White solid

A symmetric bis-glycolamide that inhibits the eIF2α phosphorylation-mediated unfolded protein response (IC₅₀ = 5 nM in a cell-reporter assay); passes through the blood-brain barrier and significantly enhances learning and memory in mice and rats.

Empirical Formula: C₂₅H₃₈O₅ Linear Formula: C₂₅H₃₈O₅ Formula Weight: 418.57 MDL Number: MFCD00072007 Purity: ≥97% (HPLC) Melting Point: 127-132 °C(lit.) Storage: 2-8°C

A selective inhibitor of PDGF receptor kinase with an IC50 value of20 µM in human bone marrow; inhibits the EGF receptor with an IC50 value of 820 µM.

The four tocopherols (α, β, .delta., and γ) and four tocotrienols (α, β, .delta., and γ) are forms of vitamin E, which is known for its antioxidant activity. Tocotrienols are found at high concentrations in palm oil and rice bran. Recent studies show tocotrienols…

Synonyms: beta:gamma-Imidoguanosine 5'-triphosphate trisodium salt hydrate; 5'-Guanylyl-imidodiphosphate trisodium salt hydrate; GMP-PNP; Gpp(NH)p CAS Number: 148892-91-5 Formula: C10H14N6Na3O13P3 · xH2O Formula Weight: 588.14 (anhydrous basis) Linear Formula: C10H14N6Na3O13P3 · xH2O…

Synonym(s): 2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide Empirical Formula: C₁₃H₁₇N₂O₂ Linear Formula: C₁₃H₁₇N₂O₂ Formula Weight: 233.29 MDL Number: MFCD00059929 Storage: 2-8°C

A potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC₅₀ values of 67 and 289 nM for the human and rat isoforms, respectively; attenuates cold allodynia following nerve injury and suppresses neuronal activity in response to mechanical stimulation.

A selective inhibitor of ASK1 (IC₅₀ = 3 μM; Ki = 500 nM); promotes survival of induced pluripotent stem cell populations and protects neurons from reactive oxygen species-induced apoptosis in a model of ischemia.

Synonyms: Fmoc-Nspe-OH Purity Limit: ≥ 99% (HPLC) Molecular Formula: C25H23NO4 Molecular Weight: 401.46 MDL No.: MFCD18782835 Appearance: White powder Optical Rotation: [a]D20 = -38 ± 2º (C=1 in DMF) Storage Temperature: Store at 0-8 °C

Formal Name: 3,4-dichloro-N-(1-methylbutyl)-benzamide CAS Number: 7497-07-6 Molecular Formula: C₁₂H₁₅Cl₂NO

Synonyms: (1R,2S)-2-(7-Oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3 carboxamido) cyclohexane-1-carboxylic acid; (1R,2S)-2-(7-Oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carboxamido)cyclohexanecarboxylic acid Molecular Formula: C20H20N4O4 Molecular Weight: 380.4 Linear…

A photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration; also inhibits autophagosome formation by directly targeting and modifying p62, a scaffold and adaptor protein that binds both…

An aminooxy analog of ornithine that irreversibly inhibits aminotransferases, including ornithine aminotransferase (Ki = 2 µM); cytotoxic to a range of organisms.

An intravenous β-lactam antibiotic that is effective against Gram-positive and Gram-negative bacteria (MICs range from 0.008-0.13 µg/ml); highly resistant to degradation by β-lactamases.

Synonym(s): 1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene Formula: C18H16N6S2 Formula weight: 380.49 Purity: 99+% CAS Number: 109511-58-2 Harmonized Tariff Code:  2930.90

A selective, orally bioavailable inhibitor of Akt1, 2, and 3 (Kis = 0.08, 2, and 2.6 nM, respectively); inhibits the proliferation of human cancer cell lines with Akt pathway activation and various cell lines derived from hematologic malignancies.

WS3 is a non-specific proliferative molecule that modulates the activity of Erb3 binding protein-1 and the IκB kinase pathway. It has been used to mediate proliferation of primary retinal pigment epithelial cells ex vivo in order to provide a renewable source of cells for transplantation in a…