Viral Gene Delivery

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Viral Gene Delivery

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  • CMV-Cre-GFP lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • EF1A-miR-211 lentivirus

    Cellomics Technology

    It has been observed that microRNA (mRNA) miR-211 plays a role in the regulation of cancer metastasis. This lentivirus expresses miR-211 under the control of the EF1A promoter.

  • CMV-MITF-H lentivirus

    Cellomics Technology

    MITF-H is an isoform of MITF (microphthalmia-associated transcription factor), a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible…

  • Set of lentivirus (Tet-driven SOX2, OCT3/4, KLF4 and C-MYC)

    Cellomics Technology

    This set contains four Tet-driven vectors: KLF4 (PLV-10026), SOX2 (PLV-10027), C-MYC (PLV-10028), and OCT3/4 (PLV-10019).

  • CMV-Firefly luciferase lentivirus (Puro)

    Cellomics Technology

    Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis.

  • NF-kB Firefly luciferase reporter lentivirus (Puro)

    Cellomics Technology

    This NF-kB reporter lentivirus expresses Firefly luciferase under the control of a minimal (m)CMV promoter and tandem repeats of the NF-kB transcriptional response element (TRE). It can be used to monitor the transcriptional activity of NF-kB.

  • TGFß/SMAD reporter lentivirus

    Cellomics Technology

    The TGFβ/SMAD reporter lentivirus is designed for monitoring the activity of the TGFβ/SMAD signaling pathway. The transforming growth factor beta (TGFβ) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell…

  • UBC-Firefly luciferase lentivirus (Neo)

    Cellomics Technology

    Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis. This lentivirus expresses Firefly luciferase under the control of UBC promoter.

  • PGK-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • FGF1 shRNA lentivirus

    Cellomics Technology

    FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF1…

  • CMV-LacZ lentivirus

    Cellomics Technology

    LacZ catalyzes the hydrolysis of the disaccharide lactose, into gluclose and galactose. The use of LacZ as a reporter gene is due to its ability to cleave the bond between galactose and the indole, 5-bromo-4-chloro-3-hydroxyindole. The cleaved indole, is an easily detectable and insoluble blue compound.

  • ViraTrap™ Lentivirus Purification Maxi Kits

    Biomiga

    The ViraTrap™ lentivirus mini purification kit is designed for fast and efficient purification of recombinant lentiviruses from lentiviral-transfected cell culture supernatant. Viral particles can be purified from cell culture of 4 to 5 T75 flasks per column. The viruses are first applied…

  • Inducible tet-on FOXG1 lentivirus

    Cellomics Technology

    Fork-head box protein G1 (FOXG1) is an evolutionarily conserved, winged-helix transcriptional repressor that that regulates neurogenesis. The FOXG1 gene has been recently implicated in the congenital form of Rett syndrome (RTT), a severe neurodevelopmental disorder.

  • EF1A-NANOG_m lentivirus

    Cellomics Technology

    NANOG is a transcription factor important for maintaining the self-renewal capacity of undifferentiated stem cells. Ectopic expression of NANOG has been used to generate iPS cells in culture. Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin that can be used…

  • Inducible tet-on PRDM1 lentivirus

    Cellomics Technology

    PR domain containing 1 with zinc finger domain (PRDM1)/B lymphocyte–induced maturation protein 1 (BLIMP1) is a transcriptional repressor. PRDM1 plays fundamentally important roles in many cell lineages and in the early development of several cell types, including B and T lymphocytes, germ…

  • Calcium indicator GCaMP3 lentivirus (CAG)

    Cellomics Technology

    Calcium is a universal second messenger regulating essential cellular signaling events in a broad range of tissues and organisms. GCaMP3 is a fusion calcium indicator of green fluorescent protein (GFP), calmodulin and the M13 domain of a myosin light chain kinase designed to show the calcium ion…

  • CAG-RFP lentivirus

    Cellomics Technology

    TurboRFP is a red (orange) fluorescent protein (ex. 553 and em. 574 nm) derived from sea anemoneEntacmaea quadricolor [Merzlyak et al., 2007]. Possessing high photostability and pH stability, TurboRFP is more than twice brighter than DsRed2. Fast TurboRFP maturation makes it clearly detectable in…

  • UBC-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • CMV-SIX6 lentivirus

    Cellomics Technology

    SIX6 (SIX Homeobox 6 ) is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. SIX6 has been showed to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2). This lentivirus expresses human SIX6…

  • Angiogenin (Ang) shRNA lentivirus

    Cellomics Technology

    Angiogenin (Ang) gene encodes a mediator of new blood vessel formation that hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. It interacts with DNA causing a promoter-like increase in the expression of rRNA. Angiogenic activity is…

  • ViraTrap™ Retrovirus Purification Mini Kits

    Biomiga

    The ViraTrap™ retrovirus mini purification kit is designed for fast and efficient purification of recombinant retroviruses from retrovirus-transfected cell culture supernatant. Up to 3 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • PGK-Cre, CMV-Firefly luciferase lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • CMV-RFP lentivirus

    Cellomics Technology

    TurboRFP is a red (orange) fluorescent protein (ex. 553 and em. 574 nm) derived from sea anemoneEntacmaea quadricolor [Merzlyak et al., 2007]. Possessing high photostability and pH stability, TurboRFP is more than twice brighter than DsRed2. Fast TurboRFP maturation makes it clearly detectable in…

  • Inducible tet-on ASCL1 lentivirus

    Cellomics Technology

    ASCL1 (Achaete-Scute Family BHLH Transcription Factor 1) is a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding.…

  • ANGPTL4 shRNA lentivirus

    Cellomics Technology

    ANGPTL4 gene encodes a glycosylated, secreted Angiopoietin-like 4 protein containing a C-terminal fibrinogen domain. The encoded protein plays an critical role in numerous cancers and it is implicated in the metastatic process by modulating vascular permeability, cancer cell motility and…

  • CMV-Cre lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • Inducible tet-on miR-302 lentivirus

    Cellomics Technology

    miR-302 is the major microRNA (mRNA) found in human embryonic stem cells and induced pluripotent stem cells.

  • Inducible tet-on NR2E3 lentivirus

    Cellomics Technology

    NR2E3, a photoreceptor-specific orphan nuclear receptor, is believed to play a pivotal role in the differentiation of photoreceptors. Mutations in NR2E3 result in syndromes characterized by excess blue cones and loss of rods: enhanced S-cone syndrome (ESCS). This lentivirus expresses human NR2E3…

  • Set of lentivirus (CMV-driven SOX2, OCT3/4, KLF4 and C-MYC)

    Cellomics Technology

    This set contains four CMV-driven vectors: SOX2 (PLV-10008), OCT3/4 (PLV-10007), KLF4 (PLV-10006) and C-MYC (PLV-10005).

  • CMV-TNFSF12 lentivirus

    Cellomics Technology

    TNFSF12 is a member of the tumor necrosis factor (TNF) ligand family. TNFSF12 is a ligand for the FN14/TWEAKER receptor involved in apoptosis and angiogenesis. This lentivirus expresses human TNFSF12 under the control of the CMV promoter.

  • Inducible tet-on Chx10 lentivirus

    Cellomics Technology

    The homeodomain transcription factor Chx10 is one of the earliest markers of the developing retina. It is required for retinal progenitor cell proliferation as well as formation of bipolar cells, a type of retinal interneuron.

  • CAG-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

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