Viral Gene Delivery

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Viral Gene Delivery

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  • This set contains four CMV-driven vectors: SOX2 (PLV-10008), OCT3/4 (PLV-10007), KLF4 (PLV-10006) and C-MYC (PLV-10005).

  • CMV-Renilla luciferase lentivirus

    Cellomics Technology

    Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Renilla luciferase refers to the enzyme that was isolated from the sea pansy, Renilla reniformis.

  • ANGPTL4 shRNA lentivirus

    Cellomics Technology

    ANGPTL4 gene encodes a glycosylated, secreted Angiopoietin-like 4 protein containing a C-terminal fibrinogen domain. The encoded protein plays an critical role in numerous cancers and it is implicated in the metastatic process by modulating vascular permeability, cancer cell motility and…

  • BrainFectIN™ enables nucleic acids delivery into central nervous system of small animals. Major difficulties with gene delivery in the central nervous system is the weakness of standard non-viral gene carriers and the limitations associated to the use of viral particles (time-consuming and…

  • The ViraTrap™ lentivirus mini purification kit is designed for fast and efficient purification of recombinant lentiviruses from lentiviral-transfected cell culture supernatant. Up to 3x10 10 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. The viruses are first…

  • Inducible tet-on Hnf4a lentivirus

    Cellomics Technology

    Hnf4a is a nuclear transcription factor which binds DNA as a homodimer. Hnf4a controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver,…

  • The ViraTrap™ lentivirus mini purification kit is designed for fast and efficient purification of recombinant lentiviruses from lentiviral-transfected cell culture supernatant. Viral particles can be purified from cell culture of 4 to 5 T75 flasks per column. The viruses are first applied…

  • In vivo ViroMag Transduction Reagent has been designed for in vivo targeted transduction with any viral vector. Virus/nanoparticles complexes can be easily administrated through various injection routes such as systemic administration (intravenous, intra-artery) or local administration…

  • CMV-Cre-GFP lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis. This lentivirus expresses Firefly luciferase under the control of CMV promoter.

  • This set contains six EF1A-driven vectors: LIN28 (PLV-10015), NANOG (PLV-10014), SOX2 (PLV-10013), OCT3/4 (PLV-10012), KLF4 (PLV-10011) and C-MYC (PLV-10010). Human elongation factor-1 alpha (EF-1 alpha) is a constitutive promoter of human origin that can be used to drive ectopic gene expression in…

  • Inducible tet-on Smad6 lentivirus

    Cellomics Technology

    Smad6 and Smad7 are inhibitory Smads induced by transforming growth factor β-Smad signal transduction pathways in a negative-feedback mechanism. Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube. Smad6 is also involved in multiple tissue differentiation…

  • The ViraTrap™ adenovirus mini purification kit is designed for fast and efficient purification of recombinant Adenovirus from adenovirus transfected cell culture supernatant. Up to 1 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • Capo Transfection Kit

    Oz Biosciences

    Calcium Phosphate (CaPO) Transfection Kit is perfect to transfect HEK 293 cells. This transfection method, first described by Graham and Van Der Ebb in 1973, has been optimized in order to reach higher transfection efficiency. The CaPO transfection kit is simple and easy to use. It allows reaching…

  • This set contains four Tet-driven vectors: KLF4 (PLV-10026), SOX2 (PLV-10027), C-MYC (PLV-10028), and OCT3/4 (PLV-10019).

  • The ViraTrap™ retrovirus mini purification kit is designed for fast and efficient purification of recombinant retroviruses from retrovirus-transfected cell culture supernatant. Up to 3 x10 12 viral particles can be purified from cell culture media of 1 to 2 T75 flasks. Traditionally the…

  • CMV-rtTA lentivirus (Neo)

    Cellomics Technology

    This strain carries the tetracycline reverse transcriptional activator (rtTA) under the control of the CMV promoter. The rtTA binds to tetracycline operator elements (TetO) in the presence of doxycycline, causing transcriptional activation of genes downstream of TetO.

  • Inducible tet-on C-MYC lentivirus

    Cellomics Technology

    MYC (C-MYC) is a regulator gene that codes for a transcription factor is believed to regulate expression of 15% of all genes. C-MYC is one of the genes that has been used to generate iPS cells in culture. This lentivirus expresses C-Myc under the control of the Tet promoter.

  • UBC-Cre-RFP lentivirus

    Cellomics Technology

    Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

  • HPSE shRNA lentivirus

    Cellomics Technology

    Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix.Heparanase (HPSE) is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. HPSE is critical regulator of angiogenesis and tumor…

  • EF1A-GFP lentivirus

    Cellomics Technology

    Green fluorescent protein (GFP), a 27 kDa protein derived from the jellyfish Aequorea victoria, emits green light (emission peak at a wavelength of 509 nm) when excited byblue light (excitation peak at a wavelength of 395 nm). Green Fluorescent Protein (GFP) has become an invaluable tool in cell…

  • Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis.

  • EF1A-OCT3/4 lentivirus

    Cellomics Technology

    OCT3/4 (POU5F1) is a transcription factor that is expressed in stem cells and germ cells. Its expression is required to sustain cell self-renewal of undifferentiated stem cells. Oct-3/4 is the most recognized marker for totipotent ES cells. Ectopic expression of OCT3/4 has been used to produce iPS…

  • CMV-MAD2 lentivirus

    Cellomics Technology

    MAD2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2 was showed to be associated with tumor differentation. This lentivirus express human MAD2 under the control of the CMV promoter.

  • Inducible tet-on Chx10 lentivirus

    Cellomics Technology

    The homeodomain transcription factor Chx10 is one of the earliest markers of the developing retina. It is required for retinal progenitor cell proliferation as well as formation of bipolar cells, a type of retinal interneuron.

  • Luciferase is an enzyme that is catalyzes the oxidation of luciferin to generate bioluminescence. Firefly luciferase refers to the enzyme that was isolated from Photinus pyralis. This lentivirus coexpresses Firefly luciferase and puromycin driven by the CMV promoter, allowing generation of Firefly…

  • CHI3L1 shRNA lentivirus

    Cellomics Technology

    In humans, CHI3L1 encodes Chitinase-3-like protein 1 (CHI3L1) that a glycoprotein member of the glycosyl hydrolase 18 family. It is a secreted glycoprotein and catalyzes the hydrolysis of chitin glycopolymer found in insect exoskeletons and fungal cell walls. The protein lacks chitinase activity…

  • OTX2 is a homeodomain transcription factor and one of the key regulator genes of photoreceptor formation. This lentivirus expresses human OTX2 under the control of the Tet promoter.

  • It has been observed that microRNA miR-204 plays a role in the regulation of cancer metastasis. This lentivirus expresses miR-204 under the control of the Tet promoter.

  • EF1A-HLF lentivirus

    Cellomics Technology

    Hepatic Leukemia Factor (HLF) is a member of the proline and acidic-rich (PAR) family, a subset of the bZIP transcription factors. Chromosomal translocation of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemia. This lentivirus expresses human HLF under the…

  • Calcium is a universal second messenger regulating essential cellular signaling events in a broad range of tissues and organisms. GCaMP3 is a fusion calcium indicator of green fluorescent protein (GFP), calmodulin and the M13 domain of a myosin light chain kinase designed to show the calcium ion…

  • Cre Recombinase is a tyrosine recombinase enzyme derived from the P1 Bacteriophage. The enzyme uses a topoisomerase I like mechanism to carry out site specific recombination events. The enzyme (38kDa) is a member of the Integrase family of site specific recombinase and it is known to catalyse the…

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