Biologically Active Small Molecules, LKT Labs, 900515-16-4

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900515-16-4 LKT Labs Biologically Active Small Molecules

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    AS-252424 is an inhibitor of p110γ PI3K that exhibits anti-inflammatory activity. In animal models of peritoneal inflammation, AS-252424 decreases leukocyte recruitment. In vascular smooth muscle cells, AS-252424 decreases endothelin A receptor-mediated activity of transient receptor…