Biologically Active Small Molecules, LKT Labs, 1143532-39-1

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1143532-39-1 LKT Labs Biologically Active Small Molecules

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    AZD-5363 is an oral pan-AKT inhibitor that causes hyperphosphorylation of AKT, locking it in a catalytically inactive state, unable to phosphorylate downstream signaling substrates such as PRAS40 and GSK-ß. This compound displays anticancer chemotherapeutic activity, inhibiting proliferation and…