A c-Myc inhibitor that binds to and distorts the bHLH-ZIP domain of c-Myc (Kd = 2.8 µM), thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity (IC₅₀ = 146 µM); cytotoxic to c-Myc-overexpressing cells lines (IC₅₀s = 15.6 and…