Biologically Active Small Molecules, Cayman Chemical, 444722-95-6

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444722-95-6 Cayman Chemical Biologically Active Small Molecules

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    A potent inhibitor of Cdk1 and Cdk2 (Kis = 9 and 6 nM; IC50s = 9.5 and 5.4 nM, respectively); 20 μM delays cell entry into mitosis and prevents proper cytokinesis, rendering binucleated cells with an abnormal number of centrosomes.