Biologically Active Small Molecules, Cayman Chemical, 27415-25-4

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27415-25-4 Cayman Chemical Biologically Active Small Molecules

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    8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 µM, respectively. When infused into…