Biologically Active Small Molecules, 90357-06-5

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90357-06-5 Biologically Active Small Molecules

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  • LKT Labs

    Bicalutimide is an inhibitor of the androgen receptor that exhibits anticancer chemotherapeutic activity. With other anti-androgens, bicalutimide decreases levels of Bcl-2, Bcl-XL, caspase-3, and PARP, induces apoptosis, and inhibits cell growth of prostate cancer cells. In similar animal models,…

  • Cayman Chemical

    A non-steroidal antiandrogen that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones.

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