Biologically Active Small Molecules, 85235-11-6

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85235-11-6 Biologically Active Small Molecules

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  • 15-deoxy-.DELTA.12,14-PGD2 is a synthetic analog of PGD2 and a potential precursor to the PPARγ ligand 15-deoxy-.DELTA.12,14-PGJ2. It possesses cytotoxic effects on L1210 mouse leukemia cells in vitro with an IC50 of 0.3 µg/ml. 15-deoxy-.DELTA.12,14-PGD2 is 10-fold more…