Biologically Active Small Molecules, 28395-03-1, LKT Labs

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LKT Labs 28395-03-1 Biologically Active Small Molecules

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    Bumetanide is a loop diuretic that is clinically used to treat congestive heart failure. Bumetanide exhibits natriuretic activity, inhibiting Na+/K+/2Cl- symporter 1 (NKCC1) and K+/Ca2+ co-transporter 2 (KCC2), decreasing fluid secretion and Na+/K+ transport. Bumetanide also exhibits anxiolytic,…