Antibiotics, Antimycotics & Preservatives, 1.0 mg
-
Nocodazole
MP BiomedicalsApplications Methyl(5-(2-thienylcarbonyl)-1H-benzimidazole-2-yl)carbamate is an anticancer drug that has been shown to interfere with the structure and function of microtubules in interphase and mitotic cells. Malignant cells may be more susceptible to the antimicrotubular effect of nocodazole…
-
Ascomycin
bioWORLDSynonyms: Immunomycin, FK520, FR-900520 Ascomycin is a macrolide immunosuppressant antibiotic. It is an ethyl analog of FK506. Ascomycin binds to the FK-506-binding protein FKBP12 and blocks the peptidyl-prolyl cis-trans isomerase activity of the protein. This bound complex inhibits…
-
Puromycin Dihydrochloride
MP BiomedicalsPuromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis…
-
MCC950 Na
MP BiomedicalsProduct Description Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and activated with ATP or nigericin, but it does not inhibit NLRP1, NLRC4, AIM2, TLR2 signaling or priming of NLRP3. Prevents…
-
Mitomycin C
MP BiomedicalsMitomycin C is the most widely used of the Mitomycin antibiotics because it is the least toxic and with the most potent antitumor activity. Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli. Mitomycin C…
-
Coelenterazine
G-BiosciencesCoelenterazine, native; 2-(p-Hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzyl-imidazo[1,2-a]pyrazin-3-(7H)-one MOLECULAR BIOLOGY GRADE Coelenterazine is a luminophore found in aquatic organisms and is the substrate for many luciferase enzymes, including Renilla reniformis, Gaussia, and…
-
Bleomycin Sulfate from Streptomyces verticillus
MP BiomedicalsBleomycin Sulfate is an atineoplastic antibiotic. A mixture of cytotonic glycopeptide antibiotics which reacts with DNA and causes strand scission; they have also been shown to have a type of oxygen transferase activity. Bleomycin A2 is the main component of the bleomycin employed clinically.…
-
Tunicamycin from Streptomyces sp.
MP BiomedicalsTunicamycin is a mixture of Tunicamycins A, B, C and D. It is a nucleoside antibiotic active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Tunicamycin has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa…
-
Valinomycin
MP BiomedicalsA metabolite with a broad antibiotic spectrum. Inhibitor of mitochonclrial action. K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes…
-
Actinomycin D from Streptomyces parvalus
MP BiomedicalsActinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity. Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of…
-
Oligomycin from Streptomyces diastatochromogenes
MP BiomedicalsOligomycin is a natural antibiotic isolated from Streptomyces diastatochromogenes, which is a mixture of oligomycins A, B, and C. Oligomycin is used as antibiotic which inhibits respiration in mitochondria. It inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary…
-
Actinomycin D
bioWORLDAntineoplastic antibiotic produced by growth of Streptomyces chrysomallys and other species of Streptomyces. A potent antibiotic that binds to the GpC steps of DNA For in vitro lab use only. Not for human use or consumption. Appearance: Solid Boiling Point: 1386.05 °C at 760…
-
Doxorubicin Hydrochloride, 10 mg
bioWORLDAntineoplastic antibiotic interferes with nucleic acid synthesis. Also acts on cell membranes. Light/moisture sensitive A Topo II inhibitor, DNA intercalator and powerful cytotoxic agent Possible risk of irreversible effects. For in vitro lab use only. Not for human use or…