Ampicillin inhibits cell wall biosynthesis (peptidoglycan cross-linking). Stock Solution of antibiotics dissolved in water should be sterilized by filtration through a 0.22 micron filter.

MOLECULAR BIOLOGY GRADE   Gentamicin efficiently inhibits growth of many Gram-positive and Gram-negative microorganisms. It does so by inhibiting protein synthesis by binding to the L6 protein of the 30S ribosomal subunit. It is also effective against mycoplasma. Recommended for use…

Spectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, it inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin. Specinomycin is used in cell…

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline. As a sulfonamide antibiotic, it functions by competitively inhibiting (i.e., by acting as a substrate analogue) enzymatic reactions involving para-aminobenzoic acid (PABA). PABA is needed in enzymatic…

Nalidixic acid sodium salt is an antibacterial agent (synthetic quinolone antibiotic), which is inhibitor of bacterial DNA polymerase (DNA gyrase) & avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae. Typically used at a…

Streptomycin Sulfate is an aminoglucoside antibiotic in which streptidine is linked glycosidically to the disaccharide streptobiosamine. Inhibit bacterial protein synthesis Gram positive bacteria Gram negative bacteria Mode of Action: Inhibits prokaryote protein synthesis. Binds to…

Chlortetracycline hydrochloride has antimicrobial action similar to tetracycline hydrochloride, but it is somewhat less active against many Gram-negative organisms. It was first isolated from the culture of Streptomyces aureofacien. Cell-permeable fluorescent probe for Ca2+ for measuring calcium…

TESTED AGAINST BOTH SENSITIVE and RESISTANT CELLS. Tetracycline Hydrochloride MOLECULAR BIOLOGY GRADE Mode of action and Anti-microbial spectrum: Tetracycline is a bacteriostatic antibiotic with activity against both gram-positive and gram-negative bacteria. Within the cell tetracycline…

TESTED AGAINST BOTH SENSITIVE and RESISTANT CELLS. MOLECULAR BIOLOGY GRADE Potency of greater than 1000 mcg/mg Mode of action and Anti-microbial spectrum: Vancomycin is a glycopeptide antibiotic that exerts its action by preventing the transfer and addition of the muramylpentapeptides that…

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…

TESTED AGAINST BOTH SENSITIVE and RESISTANT CELLS. MOLECULAR BIOLOGY GRADE Mode of action and Anti-microbial spectrum: Bacteriostatic agent against both gram negative and gram positive bacteria. Enters sensitive cells by active transport. Within the cell it binds to the 50S…

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…

Indomethacin, an anti-inflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor…

TESTED AGAINST BOTH SENSITIVE and RESISTANT CELLS. Carbenicillin Disodium   MOLECULAR BIOLOGY GRADE   Mode of action and Anti-microbial spectrum: Carbenicillin is an inhibitor of bacterial cell wall synthesis, with a similar method of action as Ampicillin. Highly effective…

Mode of Action: Novobiocin is used to study heat shock protein inhibition 1 and to produce positively supercoiled plasmid DNA. It is an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. It also is an inhibitor of retrovirus RNA-dependent DNA-polymerase. Antimicrobial spectrum:…

Tetracycline is a broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne. It has been used in studies of multidrug…

Synonyms: D-(−)-α-Aminobenzylpenicillin salt A β-lactam antibiotic with an amino group side chain attached to the penicillin structure, 6-amino-penicillanic acid. A semi-synthetic penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking)…

Cycloheximide is a glutarimide antibiotic derived from a microbial source. Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. Control of various molds and fungi in…

CAS: 13292-46-1 EC No: 236-312-0 MDL No: MFCD00151389 RTECS: VJ7000000 Powder Molecular Formula: C₄₃H₅₈N₄O₁₂ MW: 822.94 Melting Point: 194°

Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…

Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…

CAS: 56-75-7 EC No: 200-287-4 MDL No: MFCD00078159 RTECS: AB6825000 Powder Molecular Formula: C₁₁H₁₂Cl₂N₂O₅ MW: 323.13 Melting Point: 148-150°

Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. Inhibits peptide synthesis in eukaryotic organisms Used in protein synthesis in apoptosis Study of disease resistance in plant research Cycloheximide (CHX) is an antibiotic…

Chloroquine Diphosphate salt is a member of the quinolone family and a lysosomotropic agent (accumulate inside the acidic parts of the cell). This accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes. Chloroquine…

TESTED AGAINST BOTH SENSITIVE and RESISTANT CELLS. Rifampicin MOLECULAR BIOLOGY GRADE Mode of action and Anti-microbial spectrum: Rifampicin is active against gram-positive bacteria but less active against gram-negative bacteria. It interferes with the synthesis of nucleic acids by…

An antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation. …

Kanamycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria. Kanamycin is used as a selective agent for the incorporation of the NPT II (APH3) gene in plant tissues. Store dessicated at 4°C Soluble in water PubChem Chemical ID: 32943 …

Pyrimethamine is a diamino-pyrimidine and folic acid antagonist. Pyrimethamine is a medication used for protozoal infections. It is commonly used as an antimalarial drug, and is also used (combined with sulfadiazine) in the treatment of Toxoplasma gondii infections in immunocompromised patients,…

Amoxicillin is an antibacterial agent against gram-positive and gram-negative bacteria. Amoxicillin is a moderate-spectrum, β-lactam antibiotic. Amoxicillin is one of the most common antibiotics prescribed for children. It is used to study the oxygen dependent antimicrobial systems of…

CAS: 60628-96-8 EC No: 262-336-6 MDL No: MFCD00865567 RTECS: NI3517000 Powder Molecular Formula: C₂₂H₁₈N₂ MW: 310.39

TESTED AGAINST BOTH SENSITIVE and RESISTANT CELLS. MOLECULAR BIOLOGY GRADE   Mode of action and Anti-microbial spectrum: Ampicillin is an inhibitor of bacterial cell wall synthesis which acts by inhibiting the cross-linking of peptidoglycan. It is used in the selection of antibiotic…

MOLECULAR BIOLOGY GRADE NaC₁₆H₁₆N₅O₇S₂ MW: 477.5 g/mol Mode of action and Anti-microbial spectrum: Cefotaxime is an inhibitor of bacterial cell wall synthesis. High activity against gram-negative bacteria. Very often used for the…