GenScript

Human GRO-a, GRO-ß (MIP-2a), and GRO-? (MIP-2ß) are products of three distinct, nonallelichuman genes. GRO-ß and GRO-? share 90% and 86% amino acid sequence homology, respectively, with GROa. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors.GRO...

Wedge is used for holding precast gel in place.

Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the trea™ent of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks...

The product is specific for Camelid (Llama, Alpaca, and Camel) heavy chain antibodies (IgG2&3), but does not recognize the camelid conventional antibody (IgG1).

The product is specific for human CD28.

Epidermal Growth Factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through the EGF receptor (EGFR) also known as erbB1, is...

Dupilumab with trade name Dupixent, is an FDA-approved drug for the treatment of patients aged 6 years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4Rα) subunit shared by the interleukin (IL)-4...

GenScript High-Stability PCR Kit contains Green Taq DNA polymerase, 10× Taq buffer, and Stabilized dNTP Mix, 10 mM Each, all specially formulated for increased stability using our proprietary technology. The kit can be stored at 4?. for over six months or at room temperature (25?) for one month...

The HA tag is a polypeptide with the amino acid sequence YPYDVPDYA that can be added to a target protein using recombinant DNA technology. It can be fused to the N-terminus or C-terminus of the protein to facilitate detection and purification. An anti-HA tag antibody is a useful tool for the...

CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses. CTLA4 is constitutively expressed in Tregs but only upregulated in conventional T...

GenCrispr NLS-Cas9-NLS nuclease is the recombinant Streptococcus pyogenes Cas9 (wt) protein with a nucleic localization signal (NLS) on both N and C terminal, which can be used for genome editing by inducing site-specific DNA double stranded breaks. Cas9 protein forms a very stable ribonucleoprotein...

Daratumumab (Darzalex) is a human monoclonal antibody that is approved by the U.S. Food and Drug Administration for the trea™ent of multiple myeloma. Daratumumab binds to CD38 on multiple myeloma cells and induces cells to apoptose via antibody-dependent cellular cytotoxicity or...

IGF-BP-2, also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II,...

Growth-regulated Alpha Protein (GRO), also known as CXCL-1, GRO1, MGSA and SCYB1, is a chemokine belonging to the intercrine alpha (Chemokine CXC) family. It is expressed mainly by macrophages, neutrophils and epithelial cells. GRO signals through chemokine receptor CXCR1 and CXCR2, and functions to...

Integrin, alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) is an integrin protein that in human. ITGAE is expressed widely on intraepithelial lymphocyte (IEL) T cells (both aß T cells and ?d T cells) and on some peripheral regulatory T cells (Tregs). It has also been reported on...

GenScript THE ™ HA Tag Antibody, mAb, Mouse (A01244) is a highly sensitive monoclonal antibody applicable to HA-tagged fusion protein detection. It belongs to our THE ™ elite antibody collection. HA, or human influenza hemagglutinin, is a surface glycoprotein required for human influenza...

Interleukin-4 (IL-4), also known as BSF-1 and Lymphocyte stimulatory factor 1, is a secreted cytokine belonging to the IL-4/IL-13 family. It is produced by mast cells, T cells and bone marrow stromal cells. IL-4 signals through two receptor complexes: theIL4Ra/common ? chain and the IL4Ra-IL-13 Ra1...

Staphylococcal Protein A binds strongly and specifically to the Fc region of immunoglobulin molecules, especially IgG of many species such as Human, Rabbit, Pig, etc. The product contains five high affinity binding sites that are capable of interacting with the Fc region of IgG. HRP-Protein A is...

GenScript’s AmMag Wand enables protein and antibody purification from cultures up to 2 L in volume using the AmMag SA. Magnetic beads are directly incubated in cultures or lysates to bind target proteins and antibodies. Once binding is complete, the AmMag Wand is used to collect the beads and...

GenScript ExpressPlus™ PAGE Gels are high-performance precast mini polyacrylamide gels specially designed for large loading volumes. The unique design of the cassette gives better band resolution and significantly improves the sample distribution in the loading wells which increases the...

Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. It shows strain-specific heterogeneity in an N-terminal region that contains a poly-glutamine stretch. Mouse and human IL-2 exhibit cross-species activity. The receptor for IL-2 consists of three...

Ipilimumab (Yervoy) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the trea™ent of patients with unresectable or metastatic melanoma. Ipilimumab works to activate the immune system by targeting CTLA-4 (Cytotoxic T-lymphocyte protein 4), a...

GenScript's pUC57 plasmid DNA is supplied in a 50 microgram vial, ideal for genetic engineering and cloning experiments. This high-quality DNA is used to facilitate the insertion of desired genes into host cells, providing a reliable tool for molecular biology research. The plasmid is prepared to...

Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) protein 9 system provides a robust and multiplexable genome editing tool, enabling researchers to precisely manipulate specific genomic elements, and facilitating the elucidation of target gene function in...