Bio Basic Inc.

Recombinant Proteins, Bio Basic Inc.

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Bio Basic Inc. Recombinant Proteins

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  • Protein AG

    Bio Basic Inc.

  • Protein G

    Bio Basic Inc.

    Protein G binds to the constant region of many species of immunoglobulin G. It can be used to detect, quantify and purify IgG antibodies and antibody/antigen complexes. Bio Basic Inc’s Recombinant Protein G contains only IgG binding domains. The albumin-binding domain as well as cell wall and…

  • Human Epiregulin

    Bio Basic Inc.

    Epiregulin is a member of the EGF family of growth factors which includes, among others, epidermal growth factor (EGF), transforming growth factor (TGF)-alpha, amphiregulin (ARG), HB (heparinbinding)-EGF, betacellulin, and the various heregulins. It is expressed mainly in the placenta and…

  • beta-Defensin 2; Human BD-2

    Bio Basic Inc.

    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human…

  • beta-Defensin 3; Human BD-3

    Bio Basic Inc.

    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human…

  • Human Noggin

    Bio Basic Inc.

    Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other…

  • GRO-beta; Human GRO-beta (CXCL2)

    Bio Basic Inc.

    The three GRO cDNAs encode 107 amino acid precursor proteins from which the N-terminal 34 amino acid residues are cleaved to generate the mature GROs. There are no potential N-linked glycosylation sites in the amino acid sequences. GRO expression is inducible by serum or PDGF and/or by a variety of…

  • Human Growth Hormone (GH)

    Bio Basic Inc.

    Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is synthesized primarily by somatotropes in the anterior pituitary and

  • Vascular Endothelial Growth Factor 165; Murine VEGF165

    Bio Basic Inc.

    VEGF was initially purified from media conditioned by normal bovine pituitary folliculo-stellate cells and by a variety of transformed cell lines as a mitogen specific for vascular endothelial cells. It was subsequently found to be identical to an independently discovered vascular permeability…

  • Interferon-a2a; Human IFN-a2a

    Bio Basic Inc.

    At least 23 different variants of IFN-alpha are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while…

  • HB-EGF, Human

    Bio Basic Inc.

  • Granulocyte Macrophage Colony Stimulating Factor; Murine GM-CSF

    Bio Basic Inc.

    GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocytemacrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GMCSF is produced by a number of different cell types (including T cells, B cells,…

  • Fibroblast Growth Factor-Basic; Human FGF-Basic

    Bio Basic Inc.

    FGF basic (FGF-2, HBGF-2) is one of at least 22 mitogenic proteins of the FGF family, which show 35 - 60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. Storage pools within the cell or on cell surface heparan sulfate…

  • Interleukin-1 beta; Rat IL-1 beta

    Bio Basic Inc.

    IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad…

  • Leptin, Human

    Bio Basic Inc.

  • Human Lymphotactin (XCL1)

    Bio Basic Inc.

    Lymphotactin is the only known member of the C-chemokine family and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes but…

  • Protein A

    Bio Basic Inc.

  • Human Fractalkine (CX3CL1)

    Bio Basic Inc.

    Fractalkine, also named neurotactin, is a novel chemokine recently identified through bioinformatics. Fractalkine has a unique C-X3-C cysteine motif near the amino-terminus and is the first member of a fourth branch of the chemokine superfamily. Unlike other known chemokines, fractalkine is a type…

  • Fibroblast Growth Factor-Basic; Murine FGF-Basic

    Bio Basic Inc.

    FGF basic (FGF-2, HBGF-2) is one of at least 22 mitogenic proteins of the FGF family, which show 35 - 60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. Storage pools within the cell or on cell surface heparan sulfate…

  • Exendin-4

    Bio Basic Inc.

    Exendin-4 is a novel 39-amino acid peptide isolated from the venom of the Gila monster Heloderma suspectum. It shares 53% sequence homology with GLP-17-36amide and interacts with the same membrane receptor. Exendin-4 enhances glucose-depende

  • Human EPO

    Bio Basic Inc.

    Erythropoietin (EPO), a glycoprotein produced primarily by the kidney, is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The production of EPO by kidney cells is increased in response to hypoxia or anemia.…

  • Interferon-y; Human IFN-y

    Bio Basic Inc.

    Interferon-gamma (IFN-γ, also known as Type II interferon or immune interferon) is a cytokine produced primarily by T-lymphocytes and natural killer cells. The protein shares no significant homology with IFN-β or the various IFN-α family proteins. Mature IFN-γ exists as…

  • Interleukin-11; Murine IL-11

    Bio Basic Inc.

    Interleukin 11 is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive murine plasmacytoma cell line T11. IL-11 contains no cysteine residues or potential…

  • MIP-1ß/CCL4, Mouse

    Bio Basic Inc.

  • Rat SDF-1ß (CXCL12)

    Bio Basic Inc.

    SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 prote

  • Interferon-ß1b, Human IFN-ß1b

    Bio Basic Inc.

    Interferon-beta is one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity. The synthesis of IFN-beta can be induced by common inducers…

  • IL-36ß(183a.a.), Mouse

    Bio Basic Inc.

  • Glia Maturation Factor-ß; Human GMF-ß

    Bio Basic Inc.

    GMF-β, a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through…

  • Interleukin-1ß; Human IL-1ß

    Bio Basic Inc.

    IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad…

  • Recombinant Rat IL-3ß

    Bio Basic Inc.

  • Human MIP-1ß (CCL4)

    Bio Basic Inc.

  • Glia Maturation Factor-ß; Murine GMF-ß

    Bio Basic Inc.

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