UN2810, Cayman Chemical
-
Multi-Drug Resistance Assay Kit (Calcein AM)
Cayman ChemicalCayman's Multi-Drug Resistance Assay Kit provides a convenient tool for studying the modulation of cellular multi-drug resistance (MDR) machinery. The kit employs calcein AM, a cell-permeable nonfluorescent dye, which is cleaved intracellularly to yield the impermeant fluorescent molecule,…
-
Diallyl Disulfide
Cayman ChemicalAn organosulfur compound derived from allicin; converted, in the presence of thiols, to the gaseous mediator H2S; serves as a thiol-dependent H2S donor in biological systems.
-
10Z-Hymenialdisine
Cayman ChemicalA natural alkaloid that blocks potently inhibits MEK-1 (IC50 = 9 nM); also inhibits numerous kinases in vitro, most notably GSK3β, CDK1/cyclin B, CDK5/p25, CK1, and CDK2/cyclin E (IC50s = 10, 22, 28, 35, and 40 nM, respectively), as well as, less potently, ERK1/2, several…
-
Fomepizole
Cayman ChemicalA competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes metabolism of ethylene glycol and methanol to toxic metabolites; typically used as an antidote for ethylene glycol or methanol poisoning.