Source: Recombinant protein expressed in E. coli MW: 12.5 kDa

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 51.8 kDa

Source: Active recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 69.2 kDa PRMT1 is a class I arginine methyltransferase that methylates arginine residues at a number of glycine and arginine rich regions (GAR motifs) in proteins including histone H4 at arginine 3.

Source: Active recombinant N-terminal His-tagged enzyme amino acids 1-355 expressed in E. coli Mr: 43.7 kDa SIRT6 associates specifically with telomeres and functions at chromatin to decrease NF-κB signaling. Mammalian cells depleted of SIRT6 display abnormal telomere structures similar…

Active recombinant N-terminal GST-tagged protein expressed in E. coli • G9a-like protein (GLP) is a SET domain-containing methyltransferases that specifically mono- and di-methylate histone H3 at lysine 9 (H3K9).

A control peptide for tests that use Cayman’s β-Amyloid (1-8, A2V) Peptide (Item No. 10229).

A multimeric enterotoxin that catalyzes the ADP-ribosylation of the Gsα protein, which activates adenylate cyclase and increases the intracellular concentration of cAMP; causes the hypersecretion of chloride and bicarbonate ions, which results in increased fluid secretion and the severe…

Source: recombinant protein expressed in Sf21 cells Mr: 54 kDa PPARs are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation. PPARδ is a mediator of diverse…

An intact toxin that catalyzes the ADP-ribosylation and inactivation of EF-2, terminating protein synthesis and causing cell death.

Source: Active recombinant N-terminal His-tagged protein expressed in E. coli Mr: 44.6 kDa

A cytotoxin that inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion.

Source: Human recombinant PP2A catalytic subunit expressed in insect cells with an N-terminal octahistidine-tag followed by a streptactin-tag. The C-terminal leucine 309 was deleted. MW: 38.6 kDa PP2A is a divalent cation-independent protein serine/threonine phosphatase involved in regulating…

Source: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)

Source: one ampoule contains 100 µg of recombinant truncated human thioredoxin

Source: Active recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 43.7 kDa PRMT6 is a nuclear type-1 PRMT, catalyzing the formation of ω-NG-monomethylarginine and asymmetric ω-NG,NG-dimethylarginine on both histone and non-histone targets. Non-histone targets of…

Source: Active recombinant N-terminal His-tagged protein expressed in Sf21 insect cells MW: 118.3 kDa

Source: Recombinant protein expressed in E. coli WDR5 has been demonstrated to bind histone H3 by recognizing the first three amino acids of the N-terminal tail. Binding of WDR5 to a conserved arginine-containing motif in MLL-1, the so-called WDR5 interaction (“Win”) motif, promotes…

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli MW: 37.9 kDa

Source: Recombinant N-terminal GST-tagged enzyme expressed in E. coli Mr: 60.6 kDa (GST-tag); 26 kDa (native) SIRT5 is located in the mitochondrial matrix and its functions are largely still being elucidated, however a few promising substrates have been studied. SIRT5 has been shown to…

Source: Active recombinant N-terminal His-tagged enzyme amino acids 101-399 purified from E. coli Mr: 37 kDa (theoretical); 33.5 kDa (observed) SIRT3, is a mitochondrial protein that is synthesized as an enzymatically inactive protein. Human SIRT3 is activated by a matrix-processing…

Source: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli Mr: 19.1 kDa

Source: recombinant C-terminal histidine-tagged protein expressed using a baculovirus overexpression system in Sf21 cells Mr: 98.8 kDa A secreted lysophospholipase D that catalyzes the hydrolysis of LPC to generate LPA; ATX-LPA signaling is involved in a range of pathologies including tumor…

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 38.2 kDa

Source: Recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 53.5 kDa EED is a WD40 repeat-containing protein that forms part of the Polycomb repressive complex 2 (PRC2). The EED subunit does not contain methyltransferase activity. However, transcriptional repression by…

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 39.89 kDa

Source: Recombinant protein expressed in E. coli Mr: 15.5 kDa Histone H3 is one of the core nucleosomal histones. It undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.

Isolated from ram seminal vesicles.

Source: Active human recombinant C-terminal His-tagged protein preceded by a linker region and V5 epitope expressed in E. coli Mr: 34 kDa

Recombinant protein expressed in E. coli DPY-30 is a component of the MLL1 methylation complex, which interacts directly with Ash2L.

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 41.2 kDa BRDT shares homology with the RING3 protein. The two bromodomains of BRDT recognize acetylated histone H4. Loss of BRDT leads to defects in spermatogenesis. In addition to testis specific expression, BRDT was…

Source: Recombinant protein expressed in E. coli MW: 12.6 kDa

Protein Arginine Deiminases (PADs) are guanidino-modifying enzymes belonging to the amidinotransferase superfamily and are designated PAD1-4 and PAD6. PAD enzymes catalyze the conversion of specific arginine residues to citrulline in a calcium-dependent manner. All enzymes are cytosolic except for…