This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate. Download…

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and…

Pargyline is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. At 10 mg/kg iv, pargyline induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Daley rats. The…

Formula: C11H21N3NaO6P Formula weight: 345.26 Purity: 95% CAS Number: 71048-99-2 UN Number: UN2811 Hazard Class: 6.1 Packing Group: III Harmonized Tariff Code:  2941.90 Hazard Statements: H301 Toxic if swallowed. Precautionary Statements: …

Synonym(s): FK-506, Fugimycin Formula: C44H69NO12 Formula weight: 804.02 Purity: 99+% CAS Number: 104987-11-3 UN Number: UN2811 Hazard Class: 6.1 Packing Group: III Harmonized Tariff Code:  2934.99 Hazard Statements: H301 Toxic if swallowed. Precautionary Statements: …

CAS No.: 54-62-6 UN No.: UN2811 Class: 6.1 Pkg. Group: PG II

An antibacterial and coccidiostat compound that shows selective toxicity for HMLER breast cancer stem cells (IC₅₀ = ~24 μM); 8 μM treatment of 4T1 and MCF-7-Ras breast cancer cell lines decreases cancer stem cell growth ~2-fold and ~3-fold, respectively; 5 mg/kg inhibits mammary…

A cell-permeable, stable free radical that is commonly used to evaluate the ability of compounds to act as free radical scavengers or hydrogen donors and to measure the antioxidant activity of tissue extracts; followed by color change from purple (absorbance at 515-528 nm) to yellow.

Grade: USP CAS No.: 50-56-6 UN No.: UN2811 Class: 6.1 Pkg. Group: PG II

Grade: USP CAS No.: 66104-23-2 UN No.: UN2811 Class: 6.1 Pkg. Group: PG II

Synonym(s): 2'-Deoxy-5-fluorouridine, Floxuridine Formula: C9H11FN2O5 Formula weight: 246.20 Purity: 98+% CAS Number: 50-91-9 UN Number: UN2811 Hazard Class: 6.1 Packing Group: III Harmonized Tariff Code:  2934.99 Hazard Statements: H360-H341-H302 May damage fertility…

The primary active component of the heat and pain-eliciting lipid-soluble fraction of the Capsicum pepper and present in natural hot pepper extracts; elicits a sensation of burning pain by activation of TRPV1 on small, non-myelinated polymodal C-type nociceptive nerve fibers and has been widely…

A DNA alkylating agents that induces DNA interstrand and intrastrand crosslinks, cytotoxicity, and apoptosis; inhibits the growth of PC-3 prostate cancer cells with IC₅₀ values of 0.074 or 0.77 μM for sequential dosing or single dosing, respectively.

A prodrug for A-771726 that regulates T lymphocyte progression through the cell cycle by selectively inhibiting de novo pyrimidine synthesis; used to slow the disease progression of rheumatoid arthritis and as an immunosuppressive agent to prevent rejection of transplant allografts and xenografts.

Formula: C14H16N4 Formula weight: 240.31 Purity: 99% CAS Number: 99011-02-6 UN Number: UN2811 Hazard Class: 6.1 Packing Group: III Harmonized Tariff Code:  2933.99 Hazard Statements: H301-H315-H319-H335 Toxic if swallowed. Causes skin irritation. Causes serious eye…

Grade: USP CAS No.: 990-73-8 UN No.: UN2811 Class: 6.1 Pkg. Group: PG II

CAS No.: 3542-13-0 UN No.: UN2811 Class: 6.1 Pkg. Group: PG III

An inhibitor of protein synthesis in eukaryotes (IC₅₀ = 5-50 μM) that functions by interfering with translational elongation; can either induce or inhibit apoptosis depending on cell type.

CAS No.: 50-76-0 UN No.: UN2811 Class: 6.1 Pkg. Group: PG II

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034 (ISO Guide 34). This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.Certified content by quantitative NMR incl. uncertainty and expiry date are given on the…

A dipyridinyl compound that demonstrates high in vitro and ex vivo selectivity for COX-2 over COX-1.

An orally active broad spectrum antifungal agent that blocks ergosterol biosynthesis by inhibiting the fungal CYP isoform CYP51; potently inhibits the mammalian analog CYP51A1 (IC₅₀ = 63.5 nM), as well as a variety of other CYP isoforms.

An agonist of muscarinic receptors (EC₅₀ = 1.8-17 µM for human M2).

A selective α2-adrenergic receptor agonist (Ki = 183 nM) that lowers intraocular pressure by decreasing aqueous humor synthesis and increasing drainage through uveoscleral outflow; protects rat retinal ganglion cells against glutamate excitotoxicity by inhibiting glutamate release and…

A histamine H1 receptor antagonist (Ki = 9 nM) that is effective against HCV (EC₅₀ = 44 nM), preventing viral entry into host cells.

An immunomodulatory and antiproliferative compound that interacts directly with the protein CRBN (IC₅₀ = 8.5 nM), a ubiquitously-expressed E3 ligase, and DDB1 complexes.

Grade: USP CAS No.: 41372-20-7 UN No.: UN2811 Class: 6.1 Pkg. Group: PG III

Synonym(s): N -(2-Chloroethyl)- N '-(4-methylcyclohexyl)- N -nitrosourea; Methyl-CCNU Empirical Formula: C₁₀H₁₈ClN₃O₂ Linear Formula: C₁₀H₁₈ClN₃O₂ Formula Weight: 247.72 MDL Number: MFCD00133811

A second-generation antipsychotic designed to antagonize both D2 and 5-HT2A receptors with little effect on cholinergic and β-adrenergic receptors; affects α2-adrenergic and histamine H1 receptors.

A potent antagonist of dopamine receptors (IC₅₀s = 1.0 and 0.9 nM for D2 and D3, respectively);,also avidly binds α1- and α2-adrenergic receptors, histamine H1 receptor, and serotonin (5-HT) receptors 5-HT1D and 5-HT2A (Kis = 10, 80, 3.4, 19, 1.2 nM, respectively).

An HDAC inhibitor, antitumor agent that at 10 μM can induce oxidative stress contributing to apoptosis and differentiation in MCF-7 breast cancer cells; inhibits T. gondii tachyzoite propagation in human fibroblasts (EC₅₀ = 80 nM) and inhibits P. falciparum growth in human red blood…

Synonym(s): NSC 122023 Formula: C54H90N6O18 Formula weight: 1111.34 Purity: 90+% CAS Number: 2001-95-8 UN Number: UN2811 Hazard Class: 6.1 Packing Group: I Harmonized Tariff Code:  2941.90 Risk Phrases: 27/28 Very toxic in contact with skin and if swallowed. Safety…