Aceclofenac is a diclofenac analog that exhibits anti-inflammatory and analgesic activities. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that somewhat selectively inhibits COX-2; it is clinically used to treat rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.…

Bromhexine is a synthetic derivative of vasicine that exhibits mucolytic and antioxidative activities. Bromhexine increases production of serous mucus, decreases mucus viscosity, and helps cilia transport mucus out of the lungs. Bromhexine is clinically used to treat respiratory disorders…

L-Citrulline is a by product of NO formation from metabolism of L-arginine that exhibits tocolytic and antioxidative activities. L-Citrulline was originally found in watermelon. In isolated rat uteri, L-citrulline decreases uterine contractile force through stimulation of the NO-cGMP relaxant…

Butylated hydroxytoluene (BHT) is commonly used as a food and cosmetics additive; it exhibits antioxidative and anti-inflammatory activities. BHT may also display neuroprotective benefit, decreasing ethanol-induced brain damage and neurodegeneration and suppressing activation of NF-?B activation…

Butylated hydroxyanisole (BHA) exhibits antioxidative and anticancer activities. BHA is commercially used as a food additive or preservative, as its free radical scavenging ability stabilizes free radicals and prevents food spoilage. BHS also increases activity of superoxide dismutase (SOD) in…

Cinnarizine is an inhibitor of L-type voltage-gated Ca2+ channels that is clinically used to treat migraine and vertigo. Cinnarizine exhibits anticonvulsant/antiepileptic activity in combination with other therapies in animal models. This compound also inhibits D2 receptors, suppressing…