N-(4-Carbethoxyphenyl)retinamide is a retinoid that exhibits anticancer chemotherapeutic and chemopreventive activities. This compound inhibits development of stomach and oral cancers in vivo and shows some benefit in the treatment of dysplasias. Additionally, this compound induces differentiation…

3-Tert-butyl-4-hydroxyanisole (3-BHA) is one component of butylated hydroxyanisole (BHA). This compound is commonly used as a food additive; it exhibits antioxidative and anticancer activities. In leukemia cells, 3-BHA decreases the mitochondrial membrane potential, inhibits mitochondrial oxidative…

Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin G1 is cytotoxic; it inhibits DNA synthesis and induces cell cycle arrest.

6-Aminocaproic acid is a protease inhibitor that displays anticancer activity but is limited by cytotoxicity. 6-Aminocaproic acid inhibits plasmin, preventing fibrinolysis; it may exhibit pro-thrombotic activity, as it is clinically used to treat bleeding disorders.

N-Acetyl-S-(N’-phenylthiocarbamoyl)-L-cysteine (PITC) is a cysteine conjugate of N-acetyl-phenylisothiocyanate. Isothiocyanates are typically found in plants of the Brassicaceae family, including broccoli, cabbage, and radish. Isothiocyanates are best known for their antioxidative, anticancer…

Ciprofloxacin is a second generation fluoroquinolone antibiotic that exhibits antibacterial activity against both gram negative and gram positive bacteria. Ciprofloxacin inhibits DNA gyrase and topoisomerase IV, preventing DNA replication.

Cetirizine is a second generation antihistamine that exhibits anti-inflammatory, immunomodulatory, and anti-allergic activities. Cetirizine inhibits histamine H1 receptors and is used to treat dermatitis in clinical settings. In vitro, cetirizine inhib Grade: ≥99%

Azithromycin is an azalide macrolide antibiotic derived from erythromycin. Azithromycin binds the bacterial 50S ribosomal subunit, inhibiting protein translation. Azithromycin displays antibacterial, anti-fibrotic, and anti-inflammatory activities. In epithelial cells, azithromycin inhibits the…

L-Citrulline is a by product of NO formation from metabolism of L-arginine that exhibits tocolytic and antioxidative activities. L-Citrulline was originally found in watermelon. In isolated rat uteri, L-citrulline decreases uterine contractile force through stimulation of the NO-cGMP relaxant…

Anastrozole is a third generation aromatase inhibitor that suppresses synthesis of estrogen. Anastrozole exhibits anticancer chemotherapeutic activity and is clinically used to treat ER-positive breast cancer. In vitro, anastrozole inhibits proliferation of cancer cells by disrupting the…

This peptide is a protease substrate that is used to measure protease activity in vitro. Grade: ≥98%

Afatanib is an anticancer chemotherapeutic compound that has been approved to treat advanced lung cancers such as non-small cell lung cancer (NSCLC) and is in clinical trials as a potential treatment for other advanced solid tumors such as breast cance

ß-Casomorphin is a peptide fragment of casein that exhibits antioxidative and anti-fibrotic activities. In vivo, ß-casomorphin improves high glucose-induced changes in oxidative enzyme secretion and activity. ß-Casomorphin also decreases urinary glucose and protein levels as well as serum creatine…

Guanosine analog and inhibitor of RT, guanylyl cyclase, and telomerase used to treat HIV infection. Grade: ≥98%

Adrenocorticotropic hormone (ACTH) is a peptide derived from proopiomelanocortin (POMC) processed and secreted in the pituitary gland. ACTH binds and activates melanocortin-2 (MC2) receptors, stimulating cortisol production in the adrenal cortex. ACTH exhibits anti-inflammatory and immunomodulatory…

Non-fluorescent halogenated A23187 analog and Ca2+ ionophore. It induces formation of endothelial microvesicles, increasing leakage of lactate dehydrogenase and decreasing cell viability. It also induces mast cell degranulation and stimulates the acros

Anethole trithione is an oltipraz analog that is clinically used to treat xerostomia (dry mouth). Anethole trithione enhances salivary gland secretion.

Cembrenediols are diterpenes originally found in Anisomeles. These compounds exhibit antibacterial activity against Mycobacterium and antifungal activity against Colletotrichum. Grade: ≥98%

Benzydamine is a non-steroidal anti-inflammatory drug (NSAID) that also exhibits analgesic, anesthetic, and antibacterial activities. Benzydamine is clinically used to treat mucositis and sore throat. Unlike most NSAIDs, benzydamine inhibits prostaglandin synthetase, not cyclooxygenase (COX).

Aflatoxins are mycotoxins found in foods and livestock feeds that were initially produced by species of Aspergillus. Aflatoxin M1 is the hydroxylated metabolite of aflatoxin B1; it inhibits DNA synthesis and induces cell cycle arrest.

Albendazole is a benzimidazole compound that exhibits anti-parasitic and anticancer chemotherapeutic activities. Albendazole displays anti-helminthic benefit in the treatment of worm infections in humans and animals. Albendazole also displays antimitotic properties, binding the colchicine site of…

NSAID and COX-1/2 inhibitor used to decrease inflammation. It inhibits platelet aggregation and prolongs bleeding time by decreasing levels of thromboxane A2. Chronic administration decreases risk of cancer and cardiovascular events.

Azaperone is a butyrophenone tranquilizer that exhibits sedative activity through the inhibition of a-adrenergic receptors. Azaperone also inhibits dopamine receptors and histamine receptors; it also may display antiemetic, antipsychotic, antihistaminergic, and anticholinergic activities.

Chlortetracycline is a tetracycline antibiotic that also exhibits antioxidative, anti-parasitic, and neuroprotective activities. Chlortetracycline binds the 30S subunit of the bacterial ribosome, inhibiting protein synthesis; it also displays antibacterial and antimalarial properties. Additionally,…

Carbadox is an antibiotic compound used to treat livestock; it exhibits antibacterial activity against Lawsonia and Treponema. Carbadox is also used as a growth promoter and may be mutagenic.

L-Ascorbic acid is a vitamin C compound that can be found in many food and plant sources. L-Ascorbic acid exhibits antioxidative benefit and reducing activity; in vitro, it can act as a prolyl hydroxylase cofactor. Grade; ≥98%

C59 is a PORCN inhibitor that exhibits anticancer chemotherapeutic activity, inhibiting the progression of mammary tumors in vivo by downregulating Wnt signaling. Grade: ≥98%

Atriopeptin III is an analog of atrial natriuretic peptide (ANP) that exhibits vasodilatory/hypotensive and diuretic activities. In rat kidneys, atriopeptin III increases the diameter of constricted afferent arterioles, decreasing blood pressure.

Argatroban is an antithrombotic/anticoagulant compound that inhibits thrombin. Argatroban is clinically used to treat thrombosis and acute coronary syndrome.

This compound may exhibit anti-angiogenic and anticancer benefit through the potential inhibition of VEGFR2 (Flk-1), Met, RET, Axl, Ron, PDGFR, FGFR1 (Flg), and FMS-related tyrosine kinases 1, 3, and 4 (FLT1/3/4).

Berberine is an isoquinoline alkaloid found in a variety of plants, including barberry, goldenseal, Oregon grape, California poppy, and the Amur cork tree. Berberine fluoresces under ultraviolet light and is often used to stain heparin in mast cells. Berberine displays many beneficial effects,…

Benzo[a]pyrene is a polycyclic aromatic hydrocarbon (PAH) originally found in coal tar, cigarette smoke, and wood smoke. Metabolites of this compound bind DNA and induce mutations. Benzo[a]pyrene is highly carcinogenic and is used in research models to induce carcinogenesis and tumor formation.…