LKT Labs, 1204144-28-4, Biologically Active Small Molecules

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  • LKT Labs

    AZD-1208 is a Pim-1 kinase inhibitor that exhibits anticancer chemotherapeutic activity. In acute myelogenous leukemia (AML) cells, AZD-1208 induces cell cycle arrest and apoptosis, inhibiting phosphorylation of downstream targets such as Bcl-2, 4EBP1, p70S6K, and S6 and suppressing cell growth. In…