Cayman Chemical, 50 g, Chemicals
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Coomassie Blue R-250
Cayman ChemicalA dye that is commonly used in laboratories to stain or quantify proteins; typically gives blue bands on a clear background with a sensitivity of 50-100 ng/band; displays metachromasia by appearing pink-red, rather than blue, when binding certain proteins, such as collagen and histone H1.
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4-Aminopyridine
Cayman ChemicalA non-selective blocker of voltage-dependent K+-channels (Kv channels) that has greatest potency at Kv1 and Kv3 family members (IC50s = 290, 590, 195, 13, 29, and 100 µM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively); also blocks Kv2 and Kv4 subunits at millimolar concentrations.
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Probucol
Cayman ChemicalA potent antioxidant that inhibits the oxidation of cholesterol in LDL and HDL by impairing the translocation of ABCA1 from intracellular compartments to the plasma membrane.
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4-Aminobenzoic Acid (sodium salt)
Cayman ChemicalAn intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi; metabolized by a variety of enzymes in mammals, including N-acetyltransferases; may also be utilized by bacteria or fungi that are living in mammalian organisms.
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Syringic Acid
Cayman ChemicalA naturally occurring O-methylated phenolic acid that can be enzymatically degraded by some bacteria as a source of methane or methanol; inhibits aldose reductase (IC50 = 213 µg/ml), proteasome activity, and cancer cell proliferation.
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L-Ascorbic Acid 2-phosphate (magnesium salt)
Cayman ChemicalA long-acting ascorbic acid derivative that stimulates collagen expression and formation and is used in human cell culture; included in media to enhance the survival of human embryonic stem cells or drive osteogenic differentiation in human adipose stem cells and in human mesenchymal stromal/stem cells.
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Tyramine
Cayman ChemicalA trace amine that activates TAAR1 (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and human-rat chimera receptors, respectively); inhibits the release of norepinephrine and dopamine (IC50s = 40.6 and 119 nM, respectively).
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Chlorhexidine (hydrochloride)
Cayman ChemicalAn an antimicrobial agent that is often used in antiseptics and dental products such as toothpaste and mouthwash; inhibits MMP-2, -8, and -9.
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Promethazine (hydrochloride)
Cayman ChemicalA first generation histamine H1 receptor antagonist (Ki = 2.6 nM) that also inhibits muscarinic acetylcholine receptors (Ki = 22 nM); penetrates the CNS, depressing central H1 receptor activity, which may relate to its sedative properties.
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ß-Carotene
Cayman ChemicalA red/orange-colored fat-soluble terpenoid with antioxidant properties; can be cleaved to produce vitamin A and retinoic acid.
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Gallic Acid
Cayman ChemicalA trihydroxybenzoic acid that demonstrates antioxidant activity by scavenging DPPH• and HO• (IC50s = 9.4 and 191 μM, respectively) and inhibiting microsomal lipid peroxidation (IC50 = 1.51 μM).
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Luminol
Cayman ChemicalA cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation; HRP combined with H2O2 causes luminescent peroxidation of luminol; can also be oxidized, and chemiluminesce, by compounds containing iron, copper, gold, and cyanide.
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Bromophenol Blue
Cayman ChemicalCommonly used as a pH indicator, a color marker in agarose or polyacrylamide gel electrophoresis, and a dye to detect proteins and nucleic acids (absorbance at 610 nm), particularly when staining living tissues.
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Guaiacol
Cayman ChemicalGuaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of COX enzymes. It can therefore serve as a reducing co-substrate for COX reactions. The one-electron oxidation…
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ß-Glycerophosphate (sodium salt hydrate)
Cayman ChemicalA protein phosphatase inhibitor that acts as a phosphate group donor in matrix mineralization studies; 10 mM accelerates calcification of cultured vascular smooth muscle cells through an alkaline phosphatase-related mechanism.
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Palmitic Acid
Cayman ChemicalA common 16-carbon saturated fatty acid that represents 10-20% of the normal human dietary fat intake.
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Propylthiouracil
Cayman ChemicalA derivative of thiouracil which has long been used to correct hyperthyroidism; also used as a genetic marker for taste, since only some people detect it as a bitter taste.
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Vitamin K3
Cayman ChemicalA precursor to Vitamin K2 that is capable of both redox cycling and arylating nucleophilic substrates by Michael addition; used as an antihemorrhagic agent and to inhibit the proliferation of various cancer cells.
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Ampicillin (sodium salt)
Cayman ChemicalAn antibacterial antibiotic that acts by interfering directly with the biosynthesis of peptidoglycan, which constitutes the major component of the bacterial cell wall, leading to structural instability and death of bacteria; used as a selective antibiotic for resistant bacteria.
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Quercetin
Cayman ChemicalA flavonoid compound found in the bark and rinds of many plants and fruits.
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Ciprofloxacin (hydrochloride)
Cayman ChemicalA fluoroquinolone antibiotic widely used as an antimicrobial and immunomodulatory agent; functions by inhibiting DNA A fluoroquinolone antibiotic widely used as an antimicrobial and immunomodulatory agent; functions by inhibiting DNA gyrase (a type II topoisomerase) and topoisomerase IV, the…
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Tetrazolium (chloride)
Cayman ChemicalA redox indicator used to detect cellular respiration; primarily reduced by Complex I in mitochondria and, under anaerobic conditions, is completely reduced to an insoluble red 1,3,5-triphenylformazan.
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Chrysin
Cayman ChemicalA natural flavonoid with antioxidant, anti-inflammatory, and anticancer properties; inhibits HIF-1α expression in cancer cells; decreases pro-inflammatory gene expression and oxidative stress in ischemia/reperfusion injury.
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Protocatechuic Acid
Cayman ChemicalA dihydroxybenzoic acid phenolic compound that demonstrates free radical scavenging capability (IC50 = 16.3 μM) in a DPPH radical scavenging activity assay; possesses anti-inflammatory, antihyperglycemic, neuroprotective, and anticancer activities.
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Aminoguanidine (hydrochloride)
Cayman ChemicalAminoguanidine is equipotent to L-NMMA and L-NNA as an inhibitor of iNOS. The IC50 values for inhibition of mouse iNOS and rat nNOS are 5.4 and 160 µM, respectively. Aminoguanidine also inhibits induction of iNOS protein expression by endotoxin in rat macrophages.
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2-Thenoyltrifluoroacetone
Cayman ChemicalAn inhibitor of respiration in animals and bacteria; binds at the quinone reduction site of succinate:ubiquinone oxidoreductase (SQR; Complex II) in animals, preventing ubiquinone from binding; inhibits NADH fumarate reductase in bacteria; inhibits photosystem II in plants.
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Retinyl Acetate
Cayman ChemicalA natural form of vitamin A that is thermally more stable than retinol; can reduce cell proliferation and promote differentiation.
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Aspirin-50 g
Cayman ChemicalA non-selective, irreversible COX inhibitor with IC50 values of 0.75 and 1.25 mM for ovine COX-1 and COX-2, respectively.
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Sodium Butyrate
Cayman ChemicalA short chain fatty acid that inhibits HDACs, induces growth arrest, differentiation and apoptosis in cancer cells, and suppresses inflammation by reducing the expression of pro-inflammatory cytokines.
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Adenosine 5'-triphosphate (sodium salt)
Cayman ChemicalA central component of energy storage and metabolism in vivo, providing the metabolic energy to drive metabolic pumps and serving as a coenzyme in a wide array of enzymatic reactions; acts a substrate for kinases involved in cell signaling and of adenylate cyclases that produce the second messenger cAMP.
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Brilliant Blue G
Cayman ChemicalA dye which stains proteins in gels with ease and sensitivity; used in the Bradford to quantify the amount of protein in a solution; selectively inhibits P2X7 (IC50s = 10.1 nM and 265 nM for rat and human P2X7, respectively) and reduces neurological injury secondary to traumatic brain…