LPA is a potent lipid mediator that elicits its effect through four distinct receptors - LPA1/EDG-2, LPA2/EDG-4, LPA3/EDG-7 and LPA4/GPR23.{11049,13009} OMPT is a selective agonist of the LPA3 receptor. It exhibits EC50 values of 68 nM and >6.8 µM for calcium mobilization in LPA3 and…

A minor galactolipid present in oligodendrocytes and myelin, as well as comprises a major fraction of the lipids in photosynthesizing plants and green microorganisms; used as a marker for myelination.