Cayman Chemical, 499-80-9

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499-80-9 Cayman Chemical

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  • Structurally mimics 2-OG and chelates zinc; blocks the activity of 2-OG oxygenases (certain lysine demethylases and hydroxylases); inhibits several Jumonji domain-containing lysine demethylases at low micromolar concentrations and prolyl hydroxlase 1 (IC50 = 1.5 µM).