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Cayman Chemical, 100938-10-1

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100938-10-1 Cayman Chemical

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Amastatin (hydrochloride)

Cayman Chemical

A slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of AP-A (glutamyl AP; IC₅₀ = 0.54 µg/ml) but not of AP-B (arginine AP); also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic…

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