IL-13, Interleukin-13, murine (mouse): IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of…

TNF alpha, Tumor Necrosis Factor-alpha, human: Human Tumor Necrosis Factor-alpha Tumor necrosis factor alpha (TNF-α), also called cachectic, is produced by neutrophils, activated lymphocytes, macrophages, NK cells, LAK cells, astrocytes endothelial cells, smooth muscle cells and some…

GMF beta, Glia Maturation Factor beta, murine (mouse): The glia maturation factor beta belongs to the actin-binding proteins ADF family, GMF subfamily. It contains an ADF-H domain, but the research of crystallography and NMR reveals that there are structures different between human and mouse…

The Bio Basic MIP-1 Beta, CCL4, Human is suitable for use in laboratory use only. It can be stored at a temperature of -15 to 20 degree C.

The Bio Basic IL-36 Beta (153 a.a.), Murine (Mouse) is suitable for use in laboratory use only. It can be stored at a temperature of -15 to 20 degree C.

IL-1 beta, Interleukin-1 beta, porcine: Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and…

IL-36 beta (183 a.a.), murine (mouse): Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through…

FGF-basic, Fibroblast Growth Factor-basic, rat: FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and…

GMF beta, rat: Glia Maturation Factor beta (GMF-β), a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the…

sCD40 Ligand, TRAP, rHusCD40L, human: CD40 ligand, CD40L (also known as CD154, TRAP or gp39), is a 261 amino acid type II transmembrane glycoprotein belonging to the TNF family, CD40L is expressed predominantly on activated CD4+ T lymphocytes, and also found in other types of cells, like NK cells,…

FGF-basic, Fibroblast Growth Factor-basic, human: Human Fibroblast Growth Factor-basic FGF basic (FGF-2, HBGF-2) is one of at least 22 mitogenic proteins of the FGF family, which show 35 - 60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are…

IL-3 beta, Interleukin-3-beta, rat: Interleukin-3 (IL-3) is a hematopoietic growth factor that promotes the survival, differentiation, and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced…

IL-1 beta, Interleukin-1 beta, monkey (rhesus macaque): IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not…

IL-1 beta, InterleukinIL-1 beta, equine: Interleukin-1 beta (IL-1ß) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one…

IGF-1, N15 labeled, human: The insulin-like growth factors (IGFs) belonged to the insulin gene family, are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. The IGFs are similar by…

MIP-2, CXCL2, murine (mouse): Macrophage Inflammatory Protein 2 (MIP-2) was originally identified as a heparin binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. Based on its protein and DNA sequences, MIP-2 is a member of the alpha (CXC)…

IP-10, CXCL10, human: IP-10 was originally identified as an IFN-γ-inducible gene in monocytes, fibroblasts, and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1β, TNF-α, IL-12 and viruses. Additional cell types that have been shown…

SDF-1 alpha, CXCL12, human: SDF-1α and SDF-1β, members of the chemokine α subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were subsequently also cloned from…

IFN beta 1b, Interferon beta 1b, human: Human Interferon-β  Interferon-beta is one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and…

MIP-1 beta, CCL4, rat: Chemokine (C-C motif) ligand 4 encoded by the CCL4 gene, also known as macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells. In addition, it is a…

IFN gamma, Interferon gamma, murine (mouse): Interferon-gamma (IFN-γ, also known as Type II interferon or immune interferon) is a cytokine produced primarily by T-lymphocytes and natural killer cells. The protein shares no significant homology with IFN-β or the various IFN-α…

BMP-4, Bone Morphogenetic Protein-4, human: Human BMP-4 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor β (TGF-β) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation.…

NOGGIN, human: Human NOGGIN  Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action is critical for…

NOGGIN, murine (mouse): Murine NOGGIN  Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has…

MIF, Migration Inhibitor Factor, human: Migration Inhibitory Factor (MIF) is a secreted protein without a cleavable signal sequence and is secreted via a specialized, non-classical pathway. It is secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.…

SDF-1 beta, CXCL12, rat: SDF-1α and β are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV…

EGF, Epidermal Growth Factor, human: Human Epidermal Growth Factor  EGF was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting…

IL-12, Interleukin-12, human: Interleukin 12, also known as natural killer cell stimulatory factor (NKSF) or cytotoxic lymphocyte maturation factor (CLMF), is a pleiotropic cytokine originally identified in the medium of activated human B lymphoblastoid cell lines. The p40 subunit of IL-12 has…

GM-CSF, Granulocyte Macrophage Colony Stimulating Factor, murine (mouse): Mouse GM-CSF GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocytemacrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil…

SDF-1 beta, CXCL12, murine (mouse): Mouse SDF-1beta / CXCL12 SDF-1α and SDF-1β, members of the chemokine α subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. These proteins were…

Protein G binds to the constant region of many species of immunoglobulin G. It can be used to detect, quantify and purify IgG antibodies and antibody/antigen complexes. Bio Basic Inc’s Recombinant Protein G contains only IgG binding domains. The albumin-binding domain as well as cell wall and…

GRO beta, CXCL2, rat: Rat CXCL2 also named CINC-3, belongs to the CXC chemokine family. It is encoded by the gene CXCL2 and shares 90 % amino acid sequence with CXCL1/GROα. It is member of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. This chemokine is expressed by…