Chaotropic Agents

Chaotropic reagents are essential for use within the lab to aid in the denaturation of proteins by weakening the hydrophobic effect.
The single-step technique separates RNA from DNA after extraction with an acidic solution. Chaotropic agents disrupt the structure and stability of biological molecules, including protein and nucleic acid.
Protein modification reagents include urea, which is ideal for breaking hydrogen bone and disrupting the native structure of biomolecules. It also includes guanidine hydrochloride, which is perfect for disrupting interactions holding proteins together.
Formamide is an agent used in molecular biology to denature nucleic acids and can make them more accessible for analysis. Chaotropic agents are precious for the study and manipulation of biomolecules.
This is particularly useful in protein purification, nucleic acid extraction, and DNA sequencing, where the goal is to isolate or manipulate specific biomolecules.

Compare Tool

Select up to 3 products

HomeAll Products

Chaotropic Agents

1 - 9 of 9
Sort
View
Show
  • Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds, it is a strong chaotropic agent. Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a free flowing powder…

  • G-Biosciences

    A selection of strong chemicals to aid in the denaturation of proteins. Denaturants, or chaotropes, disrupt water interactions resulting in the solubilization of hydrophobic proteins and peptides. The chaotropes also act on all proteins to unfold them and alter their three-dimensional structure. …

  • G-Biosciences

    Features Synonym: Guanidinium thiocyanate CAS#: 593-84-0 Molecular Formula: CH5N3 CHNS Molecular Weight: 118.16

  • * Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins * Used in the isolation of RNA * Solubilizes insoluble or denatured proteins such as inclusion bodies * Can be used for the recovery of periplasmic proteins

  • MP Biomedicals

    Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins. This can be used as the first…

  • MP Biomedicals

  • MP Biomedicals

    Urea is the principal end product of nitrogen metabolism in most mammals, formed by the enzymatic reactions of the Kreb's cycle. Urea is a mild agent usually used in the solubilization and denaturation of proteins. It is also useful for renaturing proteins from samples already denatured…

  • G-Biosciences

    Features Synonym: Carbamide, Carbonyldiamide Linear Formula: NH2CONH2 Molecular Weight: 60.06 CAS Number: 57-13-6

  • MP Biomedicals

    Urea is the principal end product of nitrogen metabolism in most mammals, formed by the enzymatic reactions of the Kreb's cycle. Urea is a mild agent usually used in the solubilization and denaturation of proteins. It is also useful for renaturing proteins from samples already denatured with…

Compare Tool

Select up to 3 products