Biologically Active Small Molecules, UN1231, 612831-24-0
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GW 848687X
Cayman ChemicalA potent and selective EP1 receptor antagonist (IC50 = 2.5 nM), with >400-fold selectivity relative to EP2, EP3, EP4, DP1, and IP; has 30-fold selectivity over TP; shows complete anti-hyperalgesic activity in a rat model of chronic inflammatory joint pain.
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