Biologically Active Small Molecules, Cayman Chemical, UN1992
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Microcystin-LR
Cayman ChemicalMicrocystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria. They are responsible for periodic poisonings of humans and livestock drinking fresh water where the blue-green algae are endemic. Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04…
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NBD-FTY720 phenoxy (hydrochloride)
Cayman ChemicalA fluorescently-labeled analog of FTY720; methanol side chain of FTY720 that is targeted for phosphorylation by sphingosine kinases is retained, suggesting that it would likewise be phosphorylated in vivo.
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(2S)-OMPT
Cayman ChemicalLPA is a potent lipid mediator that elicits its effect through four distinct receptors - LPA1/EDG-2, LPA2/EDG-4, LPA3/EDG-7 and LPA4/GPR23.{11049,13009} OMPT is a selective agonist of the LPA3 receptor. It exhibits EC50 values of 68 nM and >6.8 µM for calcium mobilization in LPA3 and…
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Monogalactosyl Diglyceride
Cayman ChemicalA minor galactolipid present in oligodendrocytes and myelin, as well as comprises a major fraction of the lipids in photosynthesizing plants and green microorganisms; used as a marker for myelination.