Biologically Active Small Molecules, Cayman Chemical, 929016-96-6
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SB939
Cayman ChemicalA pan-HDAC inhibitor (IC50 = 77 nM in an in vitro HDAC1 activity assay) that prevents proliferation of ovarian (A2780), colon (COLO 205 and HCT116), and prostate cancer (PC-3) cell lines at IC50 values of 0.48, 0.56, 0.48, and 0.34 μM, respectively; binds all HDAC isozymes with similar affinity…
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