A potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through NaV channels (IC₅₀s = 4.1 and 5.2 nM, respectively, in frog muscle and squid axon; Kd = 1.8 nM in rat brain), blocking nerve and muscle action potentials.

A potent marine-derived neurotoxin that reversibly inhibits the inward sodium current through NaV channels (IC₅₀s = 4.1 and 5.2 nM, respectively, in frog muscle and squid axon; Kd = 1.8 nM in rat brain), blocking nerve and muscle action potentials.