Biologically Active Small Molecules, Cayman Chemical, 606143-52-6
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AZD 6244
Cayman ChemicalA potent, highly selective inhibitor of MEK1 and MEK2 (IC50 = 14-99 and 530 nM, respectively); weakly inhibits EGFR (IC50 = 7.0 µM) and has no effect on a large panel of other kinases; suppresses growth and induces apoptosis and differentiation within tumors.
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