A broad-spectrum inhibitor of 2OG oxygenases that inhibits JMJD2 demethylase activity (IC50 = 87 μM); inhibits JMJD2A, JMJD2E and the 2OG oxygenases PHF8, PHD2, and FIH (IC50s = 1.7, 2.4, 13.3, 14.3, and 20.5 μM, respectively).